MAGEA3 Protein (AA 1-314) (His tag)

Produktnummer ABIN667830

Produktdetails

Target: MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-314

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses MAGEA3 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: MAGEA3, 1-314aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 100mM NaCl

Lagerung: 4 °C

Antigendetails

Target: MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))

Andere Bezeichnung: MAGEA3 (MAGEA3 Produkte)

Synonyme: CT1.3 Protein, HIP8 Protein, HYPD Protein, MAGE3 Protein, MAGEA6 Protein, Mage-a3 Protein, MAGEA3 Protein, MAGE family member A3 Protein, melanoma antigen, family A, 3 Protein, melanoma antigen family A, 3 Protein, MAGEA3 Protein, Magea3 Protein

Hintergrund: Melanoma-associated antigen 3, also known MAGEA3, is a member of the MAGE gene family, which comprises 12 known genes, of which 6 are expressed in tumors. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGEA3 is a tumor-specific antigen widely expressed in solid and hematologic malignancies, but not in normal tissues, with the exception of testis and placenta. Therefore, MAGEA3 is an excellent candidate tumor antigen. Recombinant human MAGEA3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Melanoma-associated antigen 3, CT1.3, HIP8, HYPD, MAGE3, MZ2 D. NCBI no.: NP_005353

Molekulargewicht: 37.1 kDa (337aa) confirmed by MALDI-TOF