IMPDH1 Protein (AA 1-514) (His tag)

Produktnummer ABIN667787

Produktdetails

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-514

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses IMPDH1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: IMPDH1, 1-514aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol

Lagerung: 4 °C

Antigendetails

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Andere Bezeichnung: IMPDH1 (IMPDH1 Produkte)

Synonyme: IMPD Protein, IMPD1 Protein, LCA11 Protein, RP10 Protein, sWSS2608 Protein, B930086D20Rik Protein, IMPD 1 Protein, IMPDH 1 Protein, D3 Protein, IMPD 1b Protein, IMPDH 1b Protein, IMPDH1 Protein, id:ibd5035 Protein, si:dkey-31f5.7 Protein, wu:fa09h11 Protein, wu:fa99c03 Protein, zgc:113446 Protein, imp Protein, imp1 Protein, imp2 Protein, IMPD 1a Protein, IMPDH 1a Protein, zgc:91911 Protein, inosine monophosphate dehydrogenase 1 Protein, inosine-5'-monophosphate dehydrogenase 1 Protein, IMP (inosine 5'-monophosphate) dehydrogenase 1b Protein, IMP (inosine 5'-monophosphate) dehydrogenase 1 Protein, IMP (inosine 5'-monophosphate) dehydrogenase 1a Protein, IMPDH1 Protein, Impdh1 Protein, LOC100442769 Protein, impdh1 Protein, impdh1b Protein, impdh1.L Protein, impdh1a Protein

Hintergrund: Inosine-5'-monophosphate dehydrogenase 1, also known as IMPDH1 catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). Also, IMPDH1 is a ubiquitously expressed enzyme, functioning as a homotetramer, which catalyzed the rate-limiting step in de novo synthesis of guanine nucleotides. As such, it plays an important role in cyclic nucleoside metabolism within photoreceptors. Defects in the IMPDH1 gene are a cause of retinitis pigmentosa type 10. Recombinant human IMPDH1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: IMPD, IMPD1, LCA11, RP10, Inosine-5'-monophosphate dehydrogenase 1 IMP dehydrogenase 1. NCBI no.: NP_001136045

Molekulargewicht: 57.5 kDa (534aa), confirmed by MALDI-TOF

Pathways: Ribonucleoside Biosynthetic Process