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MAT1A Protein (AA 1-395) (His tag)

MAT1A Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Produktnummer ABIN667767
  • Target Alle MAT1A Proteine anzeigen
    MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-395
    Spezies
    • 5
    • 3
    • 3
    • 1
    Human
    Quelle
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses MAT1A Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    MAT1A, 1-395aa, Human, His tag, E.coli
    Reinheit
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product MAT1A Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 0.1M NaCl, 10% glycerol
    Lagerung
    4 °C
  • Target
    MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))
    Andere Bezeichnung
    MAT1A (MAT1A Produkte)
    Synonyme
    MAT Protein, MATA1 Protein, SAMS Protein, SAMS1 Protein, AdoMet Protein, SADE Protein, SAS Protein, AI046368 Protein, Ams Protein, wu:fi35e01 Protein, zgc:55442 Protein, methionine adenosyltransferase 1A Protein, methionine adenosyltransferase I, alpha Protein, MAT1A Protein, Mat1a Protein, mat1a Protein
    Hintergrund
    MAT1A catalyzes the formation of S-adenosyltransferase (AdoMet) for methionine catabolism in the liver. MAT1A expression also correlates with a differentiated phenotype, whereas liver cells expressing MAT2A present a dedifferentiated phenotype and lowered AdoMet synthesis. Likewise, NFkappaB and TNFalpha cause a switch from MAT1A to MAT2A expression in human hepatocellular carcinoma (HCC), which facilitates cancer cell growth. Recombinant human MAT1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: MAT, MATA1, SAMS, SAMS1, methionine adenosyltransferase I alpha, S-adenosylmethionine synthetase, MAT1A,. NCBI no.: NP_000420
    Molekulargewicht
    45.6 kDa (414aa), confirmed by MALDI-TOF.
    Pathways
    Mitotic G1-G1/S Phases, M Phase, Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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