DTNBP1 Protein (AA 1-270) (His tag)
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- Target Alle DTNBP1 Proteine anzeigen
- DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-270
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses DTNBP1 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Produktmerkmale
- Dysbindin, 1-270aa, Human, His-tagged, Recombinant, E.coli
- Reinheit
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product DTNBP1 Protein
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Dystrobrevin Binding Protein 1 (DTNBP1) (AA 1-351) protein (GST tag)
DTNBP1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Dystrobrevin Binding Protein 1 (DTNBP1) (AA 1-100) protein (GST tag)DTNBP1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Dystrobrevin Binding Protein 1 (DTNBP1) (AA 1-352) protein (Strep Tag)Crystallography grade DTNBP1 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Dystrobrevin Binding Protein 1 (DTNBP1) (AA 1-351) protein (Strep Tag)Crystallography grade DTNBP1 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Dystrobrevin Binding Protein 1 (DTNBP1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)DTNBP1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Dystrobrevin Binding Protein 1 (DTNBP1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)DTNBP1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- In 20 mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 0.5mM DTT, 20% glycerol
- Lagerung
- 4 °C
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- Target
- DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
- Andere Bezeichnung
- Dysbindin (DTNBP1 Produkte)
- Synonyme
- 5430437B18Rik Protein, AW048963 Protein, Bloc1s8 Protein, dysbindin Protein, sdy Protein, BLOC1S8 Protein, DBND Protein, HPS7 Protein, My031 Protein, SDY Protein, dtnbp1 Protein, zgc:56462 Protein, MGC83903 Protein, dbnd Protein, hps7 Protein, my031 Protein, MGC85477 Protein, DTNBP1 Protein, CG6856 Protein, Ddysb Protein, Dmel\\CG6856 Protein, si:ch211-285p6.1 Protein, dystrobrevin binding protein 1 Protein, Dysbindin Protein, dystrobrevin binding protein 1a Protein, dystrobrevin binding protein 1 L homeolog Protein, dystrobrevin binding protein 1 S homeolog Protein, dystrobrevin binding protein 1b Protein, Dtnbp1 Protein, DTNBP1 Protein, dtbp1 Protein, dtnbp1a Protein, dtnbp1.L Protein, dtnbp1.S Protein, dtnbp1 Protein, Dysb Protein, dtnbp1b Protein
- Hintergrund
- Dysbindin is a ubiquitously expressed protein that binds to alpha- and beta-dystrobrevins, components of the dystrophin-associated protein complex (DPC) in both muscle and nonmuscle cells. Dysbindin has been strongly implicated in schizophrenia (SZ) susceptibility by a series of independent genetic association and gene expression studies. Among its known functions, dysbindin is part of a protein complex, termed the biogenesis of lysosome-related organelles complex 1 (BLOC-1), the molecular components of which might be involved in the regulation of vesicular trafficking and dendrite branching. Dysbindin effects for brain volume and cortical thickness appear driven by different neurobiological processes. Recombinant human Dysbindin protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: DTNBP1, DBND, HPS7, SDY, Dystrobrevin-binding protein 1 isoform C Dystrobrevin binding protein 1, Hermansky Pudlak syndrome 7 protein. NCBI no.: NP_898862
- Molekulargewicht
- 34.6 kDa (307aa), confirmed by MALDI-TOF.
- Pathways
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling
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