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Leptin Protein (LEP)

LEP Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Produktnummer ABIN667698
  • Target Alle Leptin (LEP) Proteine anzeigen
    Leptin (LEP)
    Protein-Typ
    Recombinant
    Spezies
    • 13
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Quelle
    • 33
    • 20
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    Leptin Mouse, Recombinant, E.coli
    Reinheit
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product LEP Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In Phosphate buffered saline pH7.4
    Lagerung
    4 °C
  • Target
    Leptin (LEP)
    Andere Bezeichnung
    Leptin (LEP Produkte)
    Synonyme
    ob Protein, obese Protein, LEPD Protein, OB Protein, OBS Protein, leptin Protein, Lep Protein, LEP Protein, lep Protein
    Hintergrund
    Leptin is a 16-kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarily in the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated, resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes and infertility. Originally discovered in the mouse, the cDNA for leptin has been so far cloned from a variety of species including human, rat, cow, chicken, pig, sheep and dog. Recombinant mouse leptin was overexpressed as insoluble protein aggregate in E.coli and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: LEP, OB, OBS, Leptin Mouse, Obesity factor, Obese protein, Leptin,. NCBI no.: NP_032519
    Molekulargewicht
    16 kDa (147 aa), confirmed by MALDI-TOF.
    Pathways
    JAK-STAT Signalweg, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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