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NKIRAS1 Protein (AA 1-192) (His tag)

NKIRAS1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Produktnummer ABIN667676
  • Target Alle NKIRAS1 Proteine anzeigen
    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-192
    Spezies
    • 3
    • 1
    • 1
    • 1
    Human
    Quelle
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses NKIRAS1 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    NKIRAS1, 1-192aa , Human, His tag, E.coli
    Reinheit
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product NKIRAS1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
    Lagerung
    4 °C
  • Target
    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
    Andere Bezeichnung
    NKIRAS1 (NKIRAS1 Produkte)
    Synonyme
    NKIRAS1 Protein, KBRAS1 Protein, kappaB-Ras1 Protein, zgc:92823 Protein, kbras1 Protein, 2400004O09Rik Protein, NFKB inhibitor interacting Ras like 1 Protein, NFKB inhibitor interacting Ras-like 1 Protein, NFKB inhibitor interacting Ras-like 1 S homeolog Protein, NFKB inhibitor interacting Ras-like protein 1 Protein, NKIRAS1 Protein, nkiras1 Protein, nkiras1.S Protein, Nkiras1 Protein
    Hintergrund
    NKIRAS1, also known as NF-kappa-B inhibitor-interacting Ras-like protein 1, belongs to the small GTPase superfamily. NKIRAS1 is atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. It may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. Recombinant human NKIRAS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: NF-kappa-B inhibitor-interacting Ras-like protein 1, kappaB-Ras1, KBRAS1. NCBI no.: NP_065078
    Molekulargewicht
    23.8 kDa (212aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
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