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CHMP4A Protein (AA 1-265) (His tag)

CHMP4A Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN667654
  • Target Alle CHMP4A Proteine anzeigen
    CHMP4A (Charged Multivesicular Body Protein 4A (CHMP4A))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-265
    Spezies
    • 3
    • 1
    Human
    Quelle
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses CHMP4A Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    CHMP4A, 1-265aa, Human, His tag, E.coli
    Reinheit
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product CHMP4A Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 50% glycerol, 200mM NaCl, 0.1mM PMSF, 1mM EDTA
    Lagerung
    4 °C
  • Target
    CHMP4A (Charged Multivesicular Body Protein 4A (CHMP4A))
    Andere Bezeichnung
    CHMP4A (CHMP4A Produkte)
    Synonyme
    C14orf123 Protein, CHMP4 Protein, CHMP4B Protein, HSPC134 Protein, SHAX2 Protein, SNF7 Protein, SNF7-1 Protein, VPS32-1 Protein, VPS32A Protein, charged multivesicular body protein 4A Protein, CHMP4A Protein
    Hintergrund
    CHMP4A (Chromatin-modifying protein 4a) belongs to the SNF7 family and functions as chromatin-modifying proteins. It probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. Also during HIV-1 infection, the virus uses the ESCRT-III complex to mediate budding and exocytosis of viral proteins via the association of CHMP4 and a protein recruited by HIV-1 p6, which is present in viral Gag assembly and budding. CHMP4A expressed at higher level in heart, kidney, liver and skeletal muscle. Recombinant human CHMP4A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: chromatin modifying protein 4A, CHMP4, CHMP4B, HSPC134, SHAX2, SNF7, SNF7-1, VPS32-1, VPS32A. NCBI no.: NP_054888
    Molekulargewicht
    32.0kDa (285aa), confirmed by MALDI-TOF
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