Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

BPNT1 Protein (AA 1-308) (His tag)

BPNT1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS – PAGE SDS
Produktnummer ABIN667334
  • Target Alle BPNT1 Proteine anzeigen
    BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-308
    Spezies
    • 6
    • 2
    • 1
    Human
    Quelle
    • 3
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses BPNT1 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    BPNT1, 1-308aa, Human, His tag, E.coli
    Reinheit
    > 90 % by SDS – PAGE
    Top Product
    Discover our top product BPNT1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 5mM DTT, 0.1M NaCl.
    Lagerung
    4 °C
  • Target
    BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
    Andere Bezeichnung
    BPNT1 (BPNT1 Produkte)
    Synonyme
    BPNT1 Protein, PIP Protein, Sal3 Protein, BPntase Protein, 3'(2'), 5'-bisphosphate nucleotidase 1 Protein, bisphosphate 3'-nucleotidase 1 Protein, BPNT1 Protein, bpnt1.L Protein, Bpnt1 Protein
    Hintergrund
    BPNT1, also known as BPntase, PAP phosphatase or PIP (PAP-inositol-1,4-phosphatase), is a member of the magnesium-dependent, lithium-sensitive phosphomono-esterase superfamily. Using magnesium as a cofactor, BPNT1 catalyzes the conversion of PAPS (adenosine 3'-phosphate 5' phosphosulfate) to APS (adenosine 5'-phosphosulfate) and the conversion of PAP (3'(2')-phosphoadenosine 5' phosphate) to AMP (adenosine 5'-phosphate). Expressed ubiquitously with highest levels in brain and kidney, BPNT1 is potently inhibited by lithium, a drug used for the treatment of manic depression and bipolar affective disorder, suggesting a possible role for BPNT1 in the etiology of mood disorders. Recombinant human BPNT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: 3'(2'), 5'-bisphosphate nucleotidase 1, PIP, PAP-inositol-1,4-phosphatase. NCBI no.: NP_006076
    Molekulargewicht
    37.5 kDa (344aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
    Pathways
    Inositol Metabolic Process
Sie sind hier:
Kundenservice