DYNLL1 Protein (AA 1-89) (His tag)

Produktnummer ABIN667234

Produktdetails

Target: DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-89

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses DYNLL1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: DYNLL1, 1-89aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 1mM DTT, 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))

Andere Bezeichnung: DYNLL1 (DYNLL1 Produkte)

Synonyme: DLC1 Protein, DLC8 Protein, DNCL1 Protein, DNCLC1 Protein, LC8 Protein, LC8a Protein, PIN Protein, hdlc1 Protein, dynll2 Protein, wu:fd56c09 Protein, zgc:73406 Protein, Dlc8 Protein, Dnclc1 Protein, Pin Protein, 8kDLC Protein, lc8 Protein, dlc1 Protein, dlc8 Protein, lc8a Protein, dncl1 Protein, dnclc1 Protein, dynll1a Protein, MGC68763 Protein, CDLC2 Protein, dynll1 Protein, dynll1b Protein, pin Protein, MGC89636 Protein, dynein light chain LC8-type 1 Protein, dynein, light chain, LC8-type 1 Protein, dynein light chain LC8-type 1 S homeolog Protein, dynein light chain LC8-type 1 L homeolog Protein, Dynein light chain 1, cytoplasmic Protein, DYNLL1 Protein, dynll1 Protein, Dynll1 Protein, dynll1.S Protein, dynll1.L Protein, dlc-1 Protein

Hintergrund: DYNLL1, also known as DLC8 or PIN (protein inhibitor of neuronal nitric oxide synthase), has been identified as a protein that interacts with NOS1 resulting in NOS1 inhibition. Binding of this protein destabilizes NOS1(Neuronal nitric oxide synthase) dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. DYNLL1 is a ubiquitously expressed protein that exhibits high expression in testis and moderate expression in brain. Recombinant human DYNLL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Dynein light chain 1 cytoplasmic, DLC1, DLC8, DNCL1, DNCLC1, hdlc1, LC8, LC8a, MGC126137, MGC126138, PIN. NCBI no.: NP_003737

Molekulargewicht: 12.5 kDa (109aa) confirmed by MALDI-TOF

Pathways: M Phase, Tube Formation, Positive Regulation of Endopeptidase Activity