SIRT3 Protein (AA 118-399) (His tag)

Produktnummer ABIN667166

Produktdetails

Target: SIRT3 (Sirtuin 3 (SIRT3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 118-399

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses SIRT3 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: SIRT3, 118-399aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl

Lagerung: 4 °C

Antigendetails

Target: SIRT3 (Sirtuin 3 (SIRT3))

Andere Bezeichnung: SIRT3 (SIRT3 Produkte)

Synonyme: zgc:158774 Protein, sirtuin Protein, SIR2L3 Protein, 2310003L23Rik Protein, AI848213 Protein, Sir2l3 Protein, sirtuin 3 Protein, sirt3 Protein, SIRT3 Protein, Sirt3 Protein

Hintergrund: NAD-dependent deacetylase sirtuin-3, mitochondrial, also known as SIRT3, belongs to the sirtuin family of proteins. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have a range of molecular functions and have emerged as important proteins in aging, stress resistance and metabolic regulation. SIRT3 exhibits NAD+-dependent deacetylase activity in the mitochondria. Over-expression of SIRT3 results in increased levels of the mitochondrial uncoupling protein 1. SIRT3 protein levels are also elevated in certain breast cancers. Recombinant human SIRT3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: SIR2L3, Sirtuin3, NAD-dependent deacetylase sirtuin-3, mitochondrial. NCBI no.: NP_036371

Molekulargewicht: 33.5kDa (303aa) confirmed by MALDI-TOF