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PFN2 Protein (AA 1-140) (His tag)

PFN2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE SDS
Produktnummer ABIN667130
  • Target Alle PFN2 Proteine anzeigen
    PFN2 (Profilin 2 (PFN2))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-140
    Spezies
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 11
    • 4
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses PFN2 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    PFN2, 1-140 aa, Human, His-tagged, Recombinant, E.coli
    Reinheit
    > 95 % by SDS-PAGE
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 1mM DTT.
    Lagerung
    4 °C
  • Target
    PFN2 (Profilin 2 (PFN2))
    Andere Bezeichnung
    PFN2 (PFN2 Produkte)
    Synonyme
    D3S1319E Protein, PFL Protein, Pfn Protein, Profilin2 Protein, XProfilin2 Protein, PFN2 Protein, PRO2 Protein, Profilin-2 Protein, pfl Protein, d3s1319e Protein, profilin-2 Protein, F17A13.170 Protein, F17A13_170 Protein, PRF2 Protein, PROFILIN Protein, PROFILIN 2 Protein, profilin 2 Protein, wu:fb01g08 Protein, wu:fb54f09 Protein, wu:fd58f06 Protein, profilin 2 Protein, profilin 2 L homeolog Protein, profilin homolog 2 Protein, Profilin-2 Protein, PFN2 Protein, Pfn2 Protein, pfn2.L Protein, prf2 Protein, pfn2 Protein, pfn-2 Protein
    Hintergrund
    PFN2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. This protein is ubiquitously expressed with highest expression in kidney, brain and skeletal muscle. Like other members of the profilin family, PFN2 functions as an actin monomer-binding protein that influences the structure of the cytoskeleton by regulating actin polymerization in response to extracellular signals. At high concentrations, it prevents the polymerization of actin whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Recombinant PFN2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: PFL, Profilin 2 D3S1319E, PFN 2, PFN2, Profilin II, ProfilinII, Profilin2. NCBI no.: AAH18049
    Molekulargewicht
    17.2 kDa (160aa), confirmed by MALDI-TOF
    Pathways
    Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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