PFN2 Protein (AA 1-140) (His tag)
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- Target Alle PFN2 Proteine anzeigen
- PFN2 (Profilin 2 (PFN2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-140
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses PFN2 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Produktmerkmale
- PFN2, 1-140 aa, Human, His-tagged, Recombinant, E.coli
- Reinheit
- > 95 % by SDS-PAGE
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 1mM DTT.
- Lagerung
- 4 °C
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- Target
- PFN2 (Profilin 2 (PFN2))
- Andere Bezeichnung
- PFN2 (PFN2 Produkte)
- Synonyme
- D3S1319E Protein, PFL Protein, Pfn Protein, Profilin2 Protein, XProfilin2 Protein, PFN2 Protein, PRO2 Protein, Profilin-2 Protein, pfl Protein, d3s1319e Protein, profilin-2 Protein, F17A13.170 Protein, F17A13_170 Protein, PRF2 Protein, PROFILIN Protein, PROFILIN 2 Protein, profilin 2 Protein, wu:fb01g08 Protein, wu:fb54f09 Protein, wu:fd58f06 Protein, profilin 2 Protein, profilin 2 L homeolog Protein, profilin homolog 2 Protein, Profilin-2 Protein, PFN2 Protein, Pfn2 Protein, pfn2.L Protein, prf2 Protein, pfn2 Protein, pfn-2 Protein
- Hintergrund
- PFN2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. This protein is ubiquitously expressed with highest expression in kidney, brain and skeletal muscle. Like other members of the profilin family, PFN2 functions as an actin monomer-binding protein that influences the structure of the cytoskeleton by regulating actin polymerization in response to extracellular signals. At high concentrations, it prevents the polymerization of actin whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Recombinant PFN2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: PFL, Profilin 2 D3S1319E, PFN 2, PFN2, Profilin II, ProfilinII, Profilin2. NCBI no.: AAH18049
- Molekulargewicht
- 17.2 kDa (160aa), confirmed by MALDI-TOF
- Pathways
- Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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