Galectin 3 Protein (LGALS3) (AA 1-250) (His tag)

Produktnummer ABIN666905

Produktdetails

Target: Galectin 3 (LGALS3)

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-250

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Galectin 3 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: Galectin-3, 1-250aa, Human, His-tag, E.coli

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT.

Lagerung: 4 °C

Antigendetails

Target: Galectin 3 (LGALS3)

Andere Bezeichnung: Galectin-3 (LGALS3 Produkte)

Synonyme: CBP 35 Protein, Gal-3 Protein, Galectin-3 Protein, leg3 Protein, galactoside-binding Protein, galectin-3 Protein, lectin Protein, soluble Protein, CBP35 Protein, GAL3 Protein, GALBP Protein, GALIG Protein, L31 Protein, LGALS2 Protein, MAC2 Protein, MGC52947 Protein, MGC75803 Protein, LGALS3 Protein, gal-3 Protein, GBP Protein, L-34 Protein, Mac-2 Protein, gal3 Protein, galectin 3 Protein, Galectin-3 Protein, avian beta-defensin 3 Protein, lectin, galactoside-binding, soluble, 3 L homeolog Protein, lectin, galactoside-binding, soluble, 3 Protein, galectin 2 Protein, lectin, galactose binding, soluble 3 Protein, LGALS3 Protein, leg3 Protein, AvBD3 Protein, lgals3.L Protein, lgals3 Protein, LGALS2 Protein, Lgals3 Protein

Substanzklasse: Chemical

Hintergrund: Galectin-3 is a member of the family of animal lectins, which selectively binds beta-galactoside residues. This protein is secreted from cells by ectocytosis, which is independent of the classical secretory pathway through the endoplasmic reticulum/Golgi network. Galectin-3 has been associated with the inhibition of apoptosis and the progression of cancer. It is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. Recombinant Galectin-3 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CBP35, GAL3, GALBP, GALIG, LGALS2, MAC2., 35 kDa lectin, Carbohydrate binding protein 35, Galactose-specific lectin 3, Galactoside-binding protein, Galectin 3 internal gene,included, Galectin-3, Galectin3, GBP, IgE binding protein, IgE-binding protein, L 31, L 34, L-34 galactoside-binding lectin, L31, LGALS3, Laminin-binding protein, Lectin L-29, MAC 2 antigen, Lectin, galactose binding, soluble 3, Mac-2, Macrophage galactose-specific lectin, MGC105387. NCBI no.: NP_002297

Molekulargewicht: 28.3 kDa (270aa), confirmed by MALDI-TOF.

Pathways: RTK Signalweg