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KIR3DL1 Protein (AA 361-444) (His tag)

KIR3DL1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Produktnummer ABIN666836
  • Target Alle KIR3DL1 Produkte
    KIR3DL1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 361-444
    Spezies
    • 6
    • 2
    • 1
    Human
    Quelle
    • 4
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses KIR3DL1 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    KIR3DL1(Cytoplasmic tail, 361-444aa, His-tag , Human), Recombinant, E.coli
    Reinheit
    > 95 % by SDS - PAGE
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 25 mM Tris-HCl (pH7.5) 100mM NaCl
    Lagerung
    4 °C
  • Target
    KIR3DL1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))
    Abstract
    KIR3DL1 Produkte
    Synonyme
    KIR3DL1 Protein, KIR3DL3 Protein, CD158E1 Protein, KIR Protein, KIR3DL1/S1 Protein, NKAT3 Protein, NKB1 Protein, NKB1B Protein, Kirl1 Protein, Kirl2 Protein, Krl1 Protein, killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 Protein, uncharacterized LOC100437736 Protein, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 Protein, KIR3DL1 Protein, LOC100437736 Protein, Kir3dl1 Protein
    Hintergrund
    The three Ig-domain from of inhibitory killer cell Ig-like receptor 1(KIR3DL1,NKB1, nkat3, p70KIR) is a NK cell receptor for polymorphic HLA-B determinant. KIR3DLl recognizes the Bw4 determinant defined by sequence motifs at positins 77-83 of the HLA-B heavy chain. The cytoplasmic tail of KIR, which contains two immunoreceptor tyrosine-based inhibition motifs(ITIMs), mediates inhibitory signal transduction that prevents killer cell-mediated cytotoxicity. A His-tag fusion protein of KIR3DL1 cytoplasmic tail(361-444aa) was overexpressed as insoluble protein aggregates(inclusion bodies). This protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer. Synonyms: KIR3DL1, CD158E, NKAT3, NKB1, KIR3DL1 (Cytoplasmic tail, 361-444aa), MHC class I NK cell receptor, Natural killer-associated transcript 3, NKAT-3, p70 natural killer cell receptor clones CL-2/CL-11, HLA-BW4-specific inhibitory NK cell receptor, CD1, Killer cell immunoglobulin-like receptor 3DL1, Killer cell immunoglobulin-like receptor 3DL1 AMB11, CD158 antigen-like family member E, CD158e antigen, CD158E1, CD158E1/2, CD158E2, CL11, CL2, HLA-BW4-specific inhibitory NK cell receptor, killer cell immunoglobulin like receptor, Killer cell immunoglobulin like receptor three domains , short cytoplasmic tail, 1, Killer cell immunoglobulin like receptor three domains long cytoplasmic tail 1, KIR, KIR antigen 3DL1, KIR G1, KIR3DS1, Kirl1, Kirl2, Krl1, MGC119726, MGC119728, MGC126589, MGC126591, Natural killer associated transcript 3, Natural killer cell inhibitory receptor, NK receptor, NK-associated transcript 10, NK-associated transcript 3, NK-associated transcript 3delIg1, NKAT10, NKB1B, p70 killer cell inhibitory receptor,. NCBI no.: NP_037421
    Molekulargewicht
    15 kDa (132 aa), confirmed by MALDI-TOF.
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