GLO1 Protein (AA 1-184) (His tag)
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- Target Alle GLO1 Proteine anzeigen
- GLO1 (Glyoxalase I (GLO1))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 1-184
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Spezies
- Maus
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Quelle
- Baculovirus infected Insect Cells
- Aufreinigungstag / Konjugat
- Dieses GLO1 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MAEPQPASSG LTDETAFSCC SDPDPSTKDF LLQQTMLRIK DPKKSLDFYT RVLGLTLLQK LDFPAMKFSL YFLAYEDKND IPKDKSEKTA WTFSRKATLE LTHNWGTEDD ETQSYHNGNS DPRGFGHIGI AVPDVYSACK RFEELGVKFV KKPDDGKMKG LAFIQDPDGY WIEILNPNKI ATIILEHHHH HH
- Reinheit
- > 95 % by SDS - PAGE
- Endotoxin-Niveau
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Biological Activity Comment
- Specific activity is > 210 units/mg, and is defined as the amount of enzyme that will form 1.0 micromol of S-lactoylglutathione from methylglyoxal and reduced glutathione per minute at pH 6.5 at 25C.
- Top Product
- Discover our top product GLO1 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Bioactivity Validated
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- GLO1 (Glyoxalase I (GLO1))
- Andere Bezeichnung
- Glo1 (GLO1 Produkte)
- Synonyme
- GLOD1 Protein, GLYI Protein, 0610009E22Rik Protein, 1110008E19Rik Protein, 2510049H23Rik Protein, AW550643 Protein, GLY1 Protein, Glo-1 Protein, Glo-1r Protein, Glo-1s Protein, Glo1-r Protein, Glo1-s Protein, Qglo Protein, cb554 Protein, zgc:66035 Protein, wu:fb82g09 Protein, glod1 Protein, glyi Protein, glo1 Protein, GLO1 Protein, ATGLX1 Protein, F12F1.32 Protein, F12F1_32 Protein, GLYOXALASE I Protein, glyoxalase I homolog Protein, trypanothione-dependent glyoxalase I Protein, glyoxalase I Protein, glyoxalase 1 Protein, glyoxalase 1 L homeolog Protein, glyoxalase 1 S homeolog Protein, lactoylglutathione lyase Protein, glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein Protein, GLO1 Protein, Glo1 Protein, glo1 Protein, glo1.L Protein, glo1.S Protein, GST3 Protein, GLX1 Protein, STY1687 Protein, Bcen_2094 Protein, gloA Protein
- Hintergrund
- Glo1, also known as lactoylglutathione lyase, is a member of the glyoxalase l family. It plays a critical role in the detoxification of 2-oxoaldehydes, such as methylglyoxal. It involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. It was identified as a protein marker, which is consistently expressed to a higher extent in LAB-M than in HAB-M mice in several brain areas. Recombinant mouse Glo1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molekulargewicht
- 21.8kDa (192aa) 28-40kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_079650
- UniProt
- Q9CPU0
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