ORC6 Protein (AA 1-252) (His tag)

Produktnummer ABIN6387302

Produktdetails

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-252

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ORC6 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMGSELIG RLAPRLGLAE PDMLRKAEEY LRLSRVKCVG LSARTTETSS AVMCLDLAAS WMKCPLDRAY LIKLSGLNKE TYQSCLKSFE CLLGLNSNIG IRDLAVQFSC IEAVNMASKI LKSYESSLPQ TQQVDLDLSR PLFTSAALLS ACKILKLKVD KNKMVATSGV KKAIFDRLCK QLEKIGQQVD REPGDVATPP RKRKKIVVEA PAKEMEKVEE MPHKPQKDED LTQDYEEWKR KILENAASAQ KATAE

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.2M NaCl, 40 % glycerol, 2  mM DTT

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Andere Bezeichnung: ORC6 (ORC6 Produkte)

Synonyme: Orc6l Protein, CG1584 Protein, DmORC 6 Protein, DmORC6 Protein, Dmel\\CG1584 Protein, ORC Protein, ORC6 Protein, orc6 Protein, rDmORC Protein, ORC6L Protein, ARABIDOPSIS THALIANA ORIGIN RECOGNITION COMPLEX PROTEIN 6 Protein, ATORC6 Protein, ORIGIN RECOGNITION COMPLEX SUBUNIT 6 Protein, T2P11.3 Protein, T2P11_3 Protein, origin recognition complex protein 6 Protein, DDBDRAFT_0186183 Protein, DDBDRAFT_0233113 Protein, DDB_0186183 Protein, DDB_0233113 Protein, LOC100284755 Protein, orc6l Protein, 6720420I10Rik Protein, origin recognition complex, subunit 6 Protein, Origin recognition complex subunit 6 Protein, origin recognition complex subunit 6 Protein, origin recognition complex protein 6 Protein, origin recognition complex subunit Orc6 Protein, Orc6 Protein, ORC6 Protein, CpipJ_CPIJ005016 Protein, SJAG_01267 Protein, orcF Protein, LOC100284755 Protein, orc6 Protein

Hintergrund: Origin recognition complex subunit 6, also known as ORC6, belongs to the origin recognition complex (ORC). ORC is a highly conserved heterohexameric protein complex that associates with DNA at or near sites of initiation of DNA replication. All six ORC subunits are essential for initiation of DNA replication, and ORC may be involved in regulation of gene expression in response to stress. ORC6 is also expressed constantly throughout the cell cycle. ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble. Recombinant human ORC6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 30.5 kDa (275aa) confirmed by MALDI-TOF

NCBI Accession: NP_055136

UniProt: Q9Y5N6

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA