PARD6B Protein (His tag)
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- Target Alle PARD6B Proteine anzeigen
- PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses PARD6B Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Reinheit
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product PARD6B Protein
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- Kommentare
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Synonyms: Partitioning defective 6 homolog beta, PAR6B
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 20% glycerol, 0.2 M NaCl
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Avoid repeated freezing and thawing cycles.
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- Target
- PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))
- Andere Bezeichnung
- PARD6B (PARD6B Produkte)
- Synonyme
- PARD6B Protein, AV025615 Protein, Par6b Protein, PAR6B Protein, par-6 Protein, par6 Protein, pard6beta Protein, si:dkey-192i18.6 Protein, PAR-6 Protein, PAR-6B Protein, par-6 family cell polarity regulator beta Protein, par-6 family cell polarity regulator beta S homeolog Protein, par-6 partitioning defective 6 homolog beta (C. elegans) Protein, PARD6B Protein, Pard6b Protein, pard6b.S Protein, pard6b Protein
- Hintergrund
- Partitioning defective 6 homolog beta, also known as PARD6B, is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. Cellular asymmetry is critical for the development of multicellular organisms. PARD (partitioning-defective) proteins play important roles in asymmetric cell division and polarized growth, whereas Cdc42 and Rac mediate establishment of cell growth and polarity and contribute to oncogenic transformation by Ras. It is expressed in pancreas and in both adult and fetal kidney, and is weakly expressed in placenta and lung. Recombinant human PARD6B protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molekulargewicht
- 43.6 kDa (395aa)
- NCBI Accession
- NP_115910
- Pathways
- Cell-Cell Junction Organization
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