DKK2 Protein (His tag)
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- Target Alle DKK2 Proteine anzeigen
- DKK2 (Dickkopf 2 Homolog (DKK2))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses DKK2 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Reinheit
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product DKK2 Protein
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Dickkopf 2 Homolog (DKK2) (AA 34-100) protein (His-IF2DI Tag)
DKK2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Dickkopf 2 Homolog (DKK2) (AA 34-259) protein (His tag)DKK2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant SDS
Dickkopf 2 Homolog (DKK2) (AA 34-259) protein (His tag)Crystallography grade DKK2 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Dickkopf 2 Homolog (DKK2) (AA 34-259) protein (His tag)Crystallography grade DKK2 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Dickkopf 2 Homolog (DKK2) (AA 34-259) protein (His-SUMO Tag)DKK2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Kommentare
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Synonyms: Dickkopf-related protein 2, DKK-2
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M urea, 10% glycerol
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Avoid repeated freezing and thawing cycles.
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- Target
- DKK2 (Dickkopf 2 Homolog (DKK2))
- Andere Bezeichnung
- DKK2 (DKK2 Produkte)
- Synonyme
- DKK-2 Protein, Dkk4 Protein, zgc:171574 Protein, dickkopf WNT signaling pathway inhibitor 2 Protein, DKK2 Protein, Dkk2 Protein, dkk2 Protein
- Hintergrund
- Dickkopf-related protein 2, also known as DKK2, belongs to the dickkopf family. DKK2 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Recombinant human DKK2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molekulargewicht
- 27.6 kDa (250aa)
- NCBI Accession
- NP_055236
- Pathways
- WNT Signalweg
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