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LAG3 Protein (AA 23-450) (Fc Tag)
LAG3
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Produktnummer ABIN6253552
Produktdetails
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Target
Alle LAG3 Proteine anzeigen
LAG3
(Lymphocyte-Activation Gene 3 (LAG3))
Protein-Typ
Recombinant
Proteineigenschaft
AA 23-450
Spezies
Alle Spezies für LAG3 Proteine
Human
Quelle
Alle Expressionssysteme für LAG3 Proteine
HEK-293 Cells
Aufreinigungstag / Konjugat
Dieses LAG3 Protein ist gelabelt mit Fc Tag.
Sequenz
AA 23-450
Reinheit
>95 % as determined by SDS-PAGE.
Endotoxin-Niveau
Less than 0.01 EU per μg by the LAL method.
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Anwendungsinformationen
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Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Lyophilized
Buffer
Tris with Glycine, Arginine and NaCl, pH 7.5
Handhabung
Please avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Antigendetails
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Target
LAG3
(Lymphocyte-Activation Gene 3 (LAG3))
Andere Bezeichnung
LAG-3 (LAG3 Produkte )
Synonyme
CD223 Protein, LAG-3 Protein, Ly66 Protein, lymphocyte activating 3 Protein, lymphocyte-activation gene 3 Protein, LAG3 Protein, Lag3 Protein
Hintergrund
Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
Molekulargewicht
74.0 kDa
NCBI Accession
NP_002277
Pathways
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Cancer Immune Checkpoints
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