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Neuroglobin Protein (NGB)

NGB Spezies: Human Recombinant > 95 % as determined by SDS-PAGE.
Produktnummer ABIN622745
  • Target Alle Neuroglobin (NGB) Proteine anzeigen
    Neuroglobin (NGB)
    Protein-Typ
    Recombinant
    Spezies
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
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    Sequenz
    MERPEPELIR QSWRAVSRSP LEHGTVLFAR LFALEPDLLP LFQYNCRQFS SPEDCLSSPE FLDHIRKVML VIDAAVTNVE DLSSLEEYLA SLGRKHRAVG VKLSSFSTVG ESLLYMLEKC LGPAFTPATR AAWSQLYGAV VQAMSRGWDG E.
    Spezifität
    The amino acid sequence of the Neuroglobin human recombinant is 100% homologous to the amino acid sequence of the human Neuroglobin.
    Produktmerkmale
    Recombinant Human Neuroglobin
    Aufreinigung
    Two-step procedure using size exclusion chromatography before and after refolding.
    Reinheit
    > 95 % as determined by SDS-PAGE.
    Sterilität
    Sterile
    Top Product
    Discover our top product NGB Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Sterile filtered and lyophilized from 0.5 mg/ml in 0.05M phosphate buffer, 0.1M NaCl, pH 7.2.Add 0.2 ml of H2O and let the lyophilized pellet dissolve completely.
    Lagerung
    -20 °C
  • Target
    Neuroglobin (NGB)
    Andere Bezeichnung
    Neuroglobin (NGB Produkte)
    Synonyme
    NGB Protein, ngb Protein, neuroglobin Protein, neuroglobin L homeolog Protein, NGB Protein, Ngb Protein, ngb Protein, ngb.L Protein
    Hintergrund
    17kDa protein containing 151 amino acid residues of the Neuroglobin human Introduction: Neuroglobin, 151 amino acid residue protein, mainly expressed in vertebrate brain and retina, is a recently identified member of the globin superfamily. Augmenting O (2) supply, neuroglobin promotes survival of neurons upon hypoxic injury, potentially limiting brain damage. Moreover, neuroglobin may be a novel oxidative stress-responsive sensor for signal transduction in the brain. Neuroglobin expression is increased by neuronal hypoxia in vitro and focal cerebral ischemia in vivo, and neuronal survival after hypoxia is reduced by inhibiting neuroglobin expression with an antisense oligodeoxynucleotide and enhanced by neuroglobin overexpression. Synonyms: NGB.
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