Neuroglobin Protein (NGB)
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- Target Alle Neuroglobin (NGB) Proteine anzeigen
- Neuroglobin (NGB)
- Protein-Typ
- Recombinant
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Spezies
- Human
- Wirt
- Bitte anfragen
- Sequenz
- MERPEPELIR QSWRAVSRSP LEHGTVLFAR LFALEPDLLP LFQYNCRQFS SPEDCLSSPE FLDHIRKVML VIDAAVTNVE DLSSLEEYLA SLGRKHRAVG VKLSSFSTVG ESLLYMLEKC LGPAFTPATR AAWSQLYGAV VQAMSRGWDG E.
- Spezifität
- The amino acid sequence of the Neuroglobin human recombinant is 100% homologous to the amino acid sequence of the human Neuroglobin.
- Produktmerkmale
- Recombinant Human Neuroglobin
- Aufreinigung
- Two-step procedure using size exclusion chromatography before and after refolding.
- Reinheit
- > 95 % as determined by SDS-PAGE.
- Sterilität
- Sterile
- Top Product
- Discover our top product NGB Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Sterile filtered and lyophilized from 0.5 mg/ml in 0.05M phosphate buffer, 0.1M NaCl, pH 7.2.Add 0.2 ml of H2O and let the lyophilized pellet dissolve completely.
- Lagerung
- -20 °C
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- Target
- Neuroglobin (NGB)
- Andere Bezeichnung
- Neuroglobin (NGB Produkte)
- Synonyme
- NGB Protein, ngb Protein, neuroglobin Protein, neuroglobin L homeolog Protein, NGB Protein, Ngb Protein, ngb Protein, ngb.L Protein
- Hintergrund
- 17kDa protein containing 151 amino acid residues of the Neuroglobin human Introduction: Neuroglobin, 151 amino acid residue protein, mainly expressed in vertebrate brain and retina, is a recently identified member of the globin superfamily. Augmenting O (2) supply, neuroglobin promotes survival of neurons upon hypoxic injury, potentially limiting brain damage. Moreover, neuroglobin may be a novel oxidative stress-responsive sensor for signal transduction in the brain. Neuroglobin expression is increased by neuronal hypoxia in vitro and focal cerebral ischemia in vivo, and neuronal survival after hypoxia is reduced by inhibiting neuroglobin expression with an antisense oligodeoxynucleotide and enhanced by neuroglobin overexpression. Synonyms: NGB.
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