Retinoic Acid Early Transcript 1E (RAET1E) (AA 31-225) protein (hIgG-His-tag)
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- Target Alle Retinoic Acid Early Transcript 1E (RAET1E) Proteine anzeigen
- Retinoic Acid Early Transcript 1E (RAET1E)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 31-225
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Spezies
- Human
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Quelle
- Baculovirus infected Insect Cells
- Aufreinigungstag / Konjugat
- hIgG-His-tag
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- ADPHSLCFNF TIKSLSRPGQ PWCEAQVFLN KNLFLQYNSD NNMVKPLGLL GKKVYATSTW GELTQTLGEV GRDLRMLLCD IKPQIKTSDP STLQVEMFCQ REAERCTGAS WQFATNGEKS LLFDAMNMTW TVINHEASKI KETWKKDRGL EKYFRKLSKG DCDHWLREFL GHWEAMPEPT VSPVNASDIH WSSSSLPDVE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG KHHHHHH
- Reinheit
- > 85 % by SDS - PAGE
- Endotoxin-Niveau
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product RAET1E Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Retinoic Acid Early Transcript 1E (RAET1E)
- Andere Bezeichnung
- RAET1E (RAET1E Produkte)
- Synonyme
- LETAL Protein, N2DL-4 Protein, NKG2DL4 Protein, RAET1E2 Protein, RL-4 Protein, ULBP4 Protein, bA350J20.7 Protein, retinoic acid early transcript 1E Protein, RAET1E Protein, Raet1e Protein
- Hintergrund
- RAET1E, also known as NKG2D ligand 4 isoform 1, is a member of the RAET1/ULBP family of cell surface protein that function as ligands for NKG2D. This protein is abnormally expressed on most colon cancer and some other tumor cell lines and virus infected peripheral blood cells. It binds and co-stimulates NKG2D expressing effector cells including NK cells, NKT cells, gamma delta T cells, and CD8+ alpha beta T cells, activating cytolytic activity and/or cytokine production. Also, it functions as a stress-induced ligand for NKG2D receptor. Recombinant human RAET1E, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molekulargewicht
- 49.6kDa (437aa) 57-70kDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_631904
- UniProt
- Q8TD07
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