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Retinoic Acid Early Transcript 1E (RAET1E) (AA 31-225) protein (hIgG-His-tag)

RAET1E Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 85 % by SDS - PAGE SDS
Produktnummer ABIN5854981
  • Target Alle Retinoic Acid Early Transcript 1E (RAET1E) Proteine anzeigen
    Retinoic Acid Early Transcript 1E (RAET1E)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 31-225
    Spezies
    • 7
    • 1
    Human
    Quelle
    • 3
    • 2
    • 2
    • 1
    Baculovirus infected Insect Cells
    Aufreinigungstag / Konjugat
    hIgG-His-tag
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    ADPHSLCFNF TIKSLSRPGQ PWCEAQVFLN KNLFLQYNSD NNMVKPLGLL GKKVYATSTW GELTQTLGEV GRDLRMLLCD IKPQIKTSDP STLQVEMFCQ REAERCTGAS WQFATNGEKS LLFDAMNMTW TVINHEASKI KETWKKDRGL EKYFRKLSKG DCDHWLREFL GHWEAMPEPT VSPVNASDIH WSSSSLPDVE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG KHHHHHH
    Reinheit
    > 85 % by SDS - PAGE
    Endotoxin-Niveau
    < 1.0 EU per 1ug of protein (determined by LAL method)
    Top Product
    Discover our top product RAET1E Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    Retinoic Acid Early Transcript 1E (RAET1E)
    Andere Bezeichnung
    RAET1E (RAET1E Produkte)
    Synonyme
    LETAL Protein, N2DL-4 Protein, NKG2DL4 Protein, RAET1E2 Protein, RL-4 Protein, ULBP4 Protein, bA350J20.7 Protein, retinoic acid early transcript 1E Protein, RAET1E Protein, Raet1e Protein
    Hintergrund
    RAET1E, also known as NKG2D ligand 4 isoform 1, is a member of the RAET1/ULBP family of cell surface protein that function as ligands for NKG2D. This protein is abnormally expressed on most colon cancer and some other tumor cell lines and virus infected peripheral blood cells. It binds and co-stimulates NKG2D expressing effector cells including NK cells, NKT cells, gamma delta T cells, and CD8+ alpha beta T cells, activating cytolytic activity and/or cytokine production. Also, it functions as a stress-induced ligand for NKG2D receptor. Recombinant human RAET1E, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molekulargewicht
    49.6kDa (437aa) 57-70kDa (SDS-PAGE under reducing conditions.)
    NCBI Accession
    NP_631904
    UniProt
    Q8TD07
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