Crystallography grade
BCAM
Spezies: Human
Wirt: Insektenzellen
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
SDS, WB, ELISA, Crys
Crystallography grade
BCAM
Spezies: Human
Wirt: Insektenzellen
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
SDS, WB, ELISA, Crys
BCAM, also known as Basal cell adhesion molecule isoform 1, is an immunoglobulin superfamily protein that arises from alternate splicing of the Lutheran blood group molecule. This protein is upregulated following malignant transformation of some cell types in vivo and in vitro, thus being a candidate molecule involved in tumor progression. Also, it interacts with integrin in sickle red cells, and may potentially play a role in vaso-occlusive episodes. Recombinant human BCAM, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Molekulargewicht
83.2kDa (755aa) 70-100kDa (SDS-PAGE under reducing conditions.)