DCT Protein (AA 24-472) (His tag)
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- Target Alle DCT Proteine anzeigen
- DCT (Dopachrome Tautomerase (DCT))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 24-472
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Spezies
- Human
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Quelle
- Baculovirus infected Insect Cells
- Aufreinigungstag / Konjugat
- Dieses DCT Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- QFPRVCMTVD SLVNKECCPR LGAESANVCG SQQGRGQCTE VRADTRPWSG PYILRNQDDR ELWPRKFFHR TCKCTGNFAG YNCGDCKFGW TGPNCERKKP PVIRQNIHSL SPQEREQFLG ALDLAKKRVH PDYVITTQHW LGLLGPNGTQ PQFANCSVYD FFVWLHYYSV RDTLLGPGRP YRAIDFSHQG PAFVTWHRYH LLCLERDLQR LIGNESFALP YWNFATGRNE CDVCTDQLFG AARPDDPTLI SRNSRFSSWE TVCDSLDDYN HLVTLCNGTY EGLLRRNQMG RNSMKLPTLK DIRDCLSLQK FDNPPFFQNS TFSFRNALEG FDKADGTLDS QVMSLHNLVH SFLNGTNALP HSAANDPIFV VLHSFTDAIF DEWMKRFNPP ADAWPQELAP IGHNRMYNMV PFFPPVTNEE LFLTSDQLGY SYAIDLPVSV EETPGWPTTH HHHHH
- Reinheit
- > 90 % by SDS - PAGE
- Endotoxin-Niveau
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product DCT Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- DCT (Dopachrome Tautomerase (DCT))
- Andere Bezeichnung
- DCT (DCT Produkte)
- Synonyme
- TYRP2 Protein, RGD1564975 Protein, trp2 Protein, DT Protein, TRP-2 Protein, TRP2 Protein, Tyrp-2 Protein, Tyrp2 Protein, slaty Protein, slt Protein, zgc:109860 Protein, dopachrome tautomerase Protein, dopachrome tautomerase L homeolog Protein, DCT Protein, Dct Protein, dct Protein, dct.L Protein
- Hintergrund
- DCT, as known as L-dopachrome tautomerase isoform 1, is the tyrosinase family members. This protein plays a key role in the synthesis of the melanin pigment including tyrosinase (Tyr), tyrosinase-related protein 1 (Tyrp1). These are strongly implicated in eumelanin synthesis. The switch between the eumelanin and the pheomelanin pathways is thought to depend on the presence of cysteine. Thus, in the absence of cysteine, dopaquinone, the product of tyrosinase action, is transformed to cyclodopa (leucodopachrome) and then to dopachrome (and DOPA). Recombinant human DCT, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molekulargewicht
- 52.1kDa (455aa) 50-70kDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_001913
- UniProt
- P40126
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