PPP2R1A Protein (AA 1-589) (His tag)

Produktnummer ABIN5854332

Produktdetails

Target: PPP2R1A (Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-589

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PPP2R1A Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMAAADGD DSLYPIAVLI DELRNEDVQL RLNSIKKLST IALALGVERT RSELLPFLTD TIYDEDEVLL ALAEQLGTFT TLVGGPEYVH CLLPPLESLA TVEETVVRDK AVESLRAISH EHSPSDLEAH FVPLVKRLAG GDWFTSRTSA CGLFSVCYPR VSSAVKAELR QYFRNLCSDD TPMVRRAAAS KLGEFAKVLE LDNVKSEIIP MFSNLASDEQ DSVRLLAVEA CVNIAQLLPQ EDLEALVMPT LRQAAEDKSW RVRYMVADKF TELQKAVGPE ITKTDLVPAF QNLMKDCEAE VRAAASHKVK EFCENLSADC RENVIMSQIL PCIKELVSDA NQHVKSALAS VIMGLSPILG KDNTIEHLLP LFLAQLKDEC PEVRLNIISN LDCVNEVIGI RQLSQSLLPA IVELAEDAKW RVRLAIIEYM PLLAGQLGVE FFDEKLNSLC MAWLVDHVYA IREAATSNLK KLVEKFGKEW AHATIIPKVL AMSGDPNYLH RMTTLFCINV LSEVCGQDIT TKHMLPTVLR MAGDPVANVR FNVAKSLQKI GPILDNSTLQ SEVKPILEKL TQDQDVDVKY FAQEALTVLS LA

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: PPP2R1A (Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A))

Andere Bezeichnung: PPP2R1A (PPP2R1A Produkte)

Synonyme: PP2A-Aalpha Protein, PP2AAALPHA Protein, PR65A Protein, PR65 Protein, pp2a-aalpha Protein, pp2aaalpha Protein, ppp2r1a Protein, pr65a Protein, wu:fa02h04 Protein, zgc:56296 Protein, 6330556D22Rik Protein, PP2A Protein, ppp2r1a-a Protein, ppp2r1a-b Protein, protein phosphatase 2 scaffold subunit Aalpha Protein, protein phosphatase 2 scaffold subunit A alpha Protein, protein phosphatase 2 regulatory subunit A, alpha L homeolog Protein, protein phosphatase 2 regulatory subunit A, alpha Protein, protein phosphatase 2, regulatory subunit A, beta a Protein, serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Protein, protein phosphatase 2, regulatory subunit A, alpha isoform Protein, protein phosphatase 2, regulatory subunit A, alpha Protein, protein phosphatase 2 regulatory subunit A, alpha S homeolog Protein, PPP2R1A Protein, Ppp2r1a Protein, ppp2r1a.L Protein, ppp2r1a Protein, ppp2r1ba Protein, LOC583227 Protein, ppp2r1a.S Protein

Hintergrund: PPP2R1A also known as Serine/Threonine-Protein Phosphatase 2A 65 kDa regulatory subunit A alpha isoform, is a member of the PPP family of phosphatases, regulates a variety of essential cellular processes. PPP2R1A phosphorylation is an in vivo mechanism for regulation of the PP2A signaling complex and increased PP2A activity in heart failure. Recombinant human PPP2R1A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 67.7kDa (612aa)

NCBI Accession: NP_055040

UniProt: P30153

Pathways: PI3K-Akt Signalweg, Mitotic G1-G1/S Phases, M Phase, Hepatitis C, Toll-Like Receptors Cascades