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PRKAA1 Protein (AA 1-279) (His tag)
PRKAA1
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 85 % by SDS - PAGE
SDS
Produktnummer ABIN5854103
Produktdetails
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Target
Alle PRKAA1 Proteine anzeigen
PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
Protein-Typ
Recombinant
Proteineigenschaft
AA 1-279
Spezies
Alle Spezies für PRKAA1 Proteine
Human
Quelle
Alle Expressionssysteme für PRKAA1 Proteine
Escherichia coli (E. coli)
Aufreinigungstag / Konjugat
Dieses PRKAA1 Protein ist gelabelt mit His tag.
Applikation
SDS-PAGE (SDS)
Sequenz
MGSSHHHHHH SSGLVPRGSH MGSMRRLSSW RKMATAEKQK HDGRVKIGHY ILGDTLGVGT FGKVKVGKHE LTGHKVAVKI LNRQKIRSLD VVGKIRREIQ NLKLFRHPHI IKLYQVISTP SDIFMVMEYV SGGELFDYIC KNGRLDEKES RRLFQQILSG VDYCHRHMVV HRDLKPENVL LDAHMNAKIA DFGLSNMMSD GEFLRTSCGS PNYAAPEVIS GRLYAGPEVD IWSSGVILYA LLCGTLPFDD DHVPTLFKKI CDGIFYTPQY LNPSVISLLK HMLQVDPMKR ATIKDIREHE WF
Reinheit
> 85 % by SDS - PAGE
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid, In 20 mM Tris-HCl buffer( pH 8.0) containing 10 % glycerol
Lagerung
4 °C,-20 °C,-80 °C
Informationen zur Lagerung
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Antigendetails
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Target
PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
Andere Bezeichnung
PRKAA,1 (PRKAA1 Produkte )
Synonyme
AMPK Protein, AMPKa1 Protein, cb116 Protein, im:7154392 Protein, sb:cb130 Protein, wu:fa94c10 Protein, AMPK1 Protein, AMPKalpha1 Protein, AI194361 Protein, AI450832 Protein, AL024255 Protein, C130083N04Rik Protein, ampk Protein, ampka1 Protein, PRKAA1 Protein, protein kinase AMP-activated catalytic subunit alpha 1 Protein, protein kinase, AMP-activated, alpha 1 catalytic subunit Protein, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog Protein, PRKAA1 Protein, prkaa1 Protein, Prkaa1 Protein, prkaa1.L Protein
Hintergrund
PRKAA1 also known as 5-AMP-activated protein kinase catalytic subunit alpha-1 isoform 1. PRKAA1 is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinasen activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Recombinant human PRKAA1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Molekulargewicht
34.3kDa (302aa)
NCBI Accession
NP_006242
UniProt
Q13131
Pathways
AMPK Signaling , Carbohydrate Homeostasis , Regulation of Carbohydrate Metabolic Process , Warburg Effekt
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