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PLA2G7 Protein (AA 47-441) (His tag)

Lp-PLA2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Produktnummer ABIN5854006
  • Target Alle PLA2G7 (Lp-PLA2) Proteine anzeigen
    PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 47-441
    Spezies
    • 10
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Quelle
    • 9
    • 6
    • 4
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses PLA2G7 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    MGSSHHHHHH SSGLVPRGSH MGSAAASFGQ TKIPRGNGPY SVGCTDLMFD HTNKGTFLRL YYPSQDNDRL DTLWIPNKEY FWGLSKFLGT HWLMGNILRL LFGSMTTPAN WNSPLRPGEK YPLVVFSHGL GAFRTLYSAI GIDLASHGFI VAAVEHRDRS ASATYYFKDQ SAAEIGDKSW LYLRTLKQEE ETHIRNEQVR QRAKECSQAL SLILDIDHGK PVKNALDLKF DMEQLKDSID REKIAVIGHS FGGATVIQTL SEDQRFRCGI ALDAWMFPLG DEVYSRIPQP LFFINSEYFQ YPANIIKMKK CYSPDKERKM ITIRGSVHQN FADFTFATGK IIGHMLKLKG DIDSNVAIDL SNKASLAFLQ KHLGLHKDFD QWDCLIEGDD ENLIPGTNIN TTNQHIMLQN SSGIEKYN
    Reinheit
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product Lp-PLA2 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Liquid. Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol,
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
    Andere Bezeichnung
    PLA2G7 (Lp-PLA2 Produkte)
    Synonyme
    LDL-PLA2 Protein, LP-PLA2 Protein, PAFAD Protein, PAFAH Protein, Lp-PLA2 Protein, PAF-AH Protein, R75400 Protein, zgc:77563 Protein, phospholipase A2 group VII Protein, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) Protein, PLA2G7 Protein, Pla2g7 Protein, pla2g7 Protein
    Hintergrund
    PLA2G7(platelet-activating factor acetylhydrolase), also known as lipoprotein-associated phospholipase A2, is a phospholipase A2 enzyme. It is a secreted enzyme which catalyzes the degradation of platelet-activating factor to biologically inactive products. This protein is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. In the blood, PLA2G7 goes mainly with LDL and less than 20 % is coupled with HDL. It is implicated in the development of atherosclerosis and is also a marker for cardiac disease. It might have a major physiologic effect in the presence of inflammatory bodily responses. Recombinant human PLA2G7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
    Molekulargewicht
    47.2 kDa(418aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_001161829
    UniProt
    Q13093
    Pathways
    Peptide Hormone Metabolism
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