Crystallography grade
SERPINB8
Spezies: Human
Wirt: Insektenzellen
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ELISA, WB, SDS, Crys
pi8 Protein, cap2 Protein, CAP-2 Protein, CAP2 Protein, NK10 Protein, Spi8 Protein, ovalbumin Protein, PI8 Protein, serpin family B member 8 Protein, serpin B8 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 8 Protein, serine (or cysteine) peptidase inhibitor, clade B, member 8 Protein, Serpinb8 Protein, SERPINB8 Protein, LOC607205 Protein, serpinb8 Protein, LOC100424017 Protein
Hintergrund
The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. SERPINB8 is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1, is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position. Recombinant human SERPINB8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.