NFU1 Protein (AA 10-254) (His tag)

Produktnummer ABIN5853977

Produktdetails

Target: NFU1 (NFU1 Iron-Sulfur Cluster Scaffold (NFU1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 10-254

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses NFU1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSGAAAVAA GLRRRFCHML KNPYTIKKQP LHQFVQRPLF PLPAAFYHPV RYMFIQTQDT PNPNSLKFIP GKPVLETRTM DFPTPAAAFR SPLARQLFRI EGVKSVFFGP DFITVTKENE ELDWNLLKPD IYATIMDFFA SGLPLVTEET PSGEAGSEED DEVVAMIKEL LDTRIRPTVQ EDGGDVIYKG FEDGIVQLKL QGSCTSCPSS IITLKNGIQN MLQFYIPEVE GVEQVMDDES DEKEANSP

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate buffer saline (  pH 7.4) containing 20 % glycerol 1  mM DTT

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: NFU1 (NFU1 Iron-Sulfur Cluster Scaffold (NFU1))

Andere Bezeichnung: NFu1 (NFU1 Produkte)

Synonyme: HIRIP Protein, HIRIP5 Protein, MMDS1 Protein, NIFUC Protein, Nfu Protein, NifU Protein, 0610006G17Rik Protein, CGI-33 Protein, Hirip5 Protein, NFU1 iron-sulfur cluster scaffold Protein, NFU1 Protein, Nfu1 Protein

Hintergrund: NFu1 is a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. This protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of bmultiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Recombinant human NFu1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 29.9 kDa (268aa) confirmed by MALDI-TOF

NCBI Accession: NP_001002755

UniProt: Q9UMS0