DPY30 Protein (AA 1-99) (His tag)
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- Target Alle DPY30 Proteine anzeigen
- DPY30 (Dpy-30 Homolog (DPY30))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-99
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses DPY30 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MGSSHHHHHH SSGLVPRGSH MGSMEPEQML EGQTQVAENP HSEYGLTDNV ERIVENEKIN AEKSSKQKVD LQSLPTRAYL DQTVVPILLQ GLAVLAKERP PNPIEFLASY LLKNKAQFED RN
- Reinheit
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product DPY30 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.2M NaCl, 30 % glycerol, 2 mM DTT
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- DPY30 (Dpy-30 Homolog (DPY30))
- Andere Bezeichnung
- DPY30 (DPY30 Produkte)
- Synonyme
- HDPY-30 Protein, Saf19 Protein, 2810410M20Rik Protein, C87842 Protein, Aip1 Protein, dpy-30, histone methyltransferase complex regulatory subunit Protein, dpy-30 histone methyltransferase complex regulatory subunit Protein, DPY30 Protein, Dpy30 Protein
- Hintergrund
- As part of the MLL1/MLL complex, DPY30 is involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. This protein may play some role in histone H3 acetylation. In a teratocarcinoma cell, it plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. DPY30 may also play an indirect or direct role in endosomal transport. Recombinant human DPY30 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molekulargewicht
- 13.6 kDa (122aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_115963
- UniProt
- Q9C005
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