HCV Core Protein Protein (AA 1-120) (His tag)

Produktnummer ABIN5853816

Produktdetails

Target: HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-120

Spezies: Hepatitis C Virus (HCV)

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses HCV Core Protein Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MSTNPKPQRK TKRNTNRRPQ DVKFPGGGQI VGGVYLLPRR GPRLGVRATR KTSERSQPRG RRQPIPKARR PEGRTWAQPG YPWPLYGNEG CGWAGWLLSP RGSRPSWGPT DPRRRSRNLG

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Denatured

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M urea, 10 % glycerol

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))

Andere Bezeichnung: HCV-Core (HCV C Produkte)

Substanzklasse: Viral Protein

Hintergrund: HCV-Core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. It modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit and also regulates many host cellular functions such as signaling pathways and apoptosis. HCV-Core prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. Recombinant Hepatitis C virus Core protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molekulargewicht: 15.7 kDa (140aa)