Neurogranin Protein (NRGN) (AA 1-78) (His tag)
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- Target Alle Neurogranin (NRGN) Proteine anzeigen
- Neurogranin (NRGN)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-78
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses Neurogranin Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MGSSHHHHHH SSGLVPRGSH MGSMDCCTEN ACSKPDDDIL DIPLDDPGAN AAAAKIQASF RGHMARKKIK SGERGRKGPG PGGPGGAGVA RGGAGGGPSG D
- Reinheit
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product NRGN Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- Liquid. 20 mM Tris-HCl buffer ( pH 7.0) containing 30 % glycerol 0.1 mM PMSF,1 mM EDTA
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Neurogranin (NRGN)
- Andere Bezeichnung
- NRGN (NRGN Produkte)
- Synonyme
- RC3 Protein, hng Protein, 0710001B06Rik Protein, AI838505 Protein, NG Protein, NG/RC3 Protein, Pss1 Protein, R75334 Protein, zgc:158686 Protein, neurogranin Protein, neurogranin (protein kinase C substrate, RC3) b Protein, NRGN Protein, Nrgn Protein, nrgnb Protein
- Hintergrund
- NRGN, also known as Neurogranin, is a calmodulin-binding protein expressed exclusively in the brain, particularly in dendritic spines, and participating in the protein kinase C signaling pathway. This protein is the main postsynaptic protein regulating the availability of calmodulin, binding to it in the absence of calcium. Phosphorylation by protein kinase C lowers its binding ability. Recombinant human NRGN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography
- Molekulargewicht
- 10.0 kDa(101aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
- NCBI Accession
- NP_001119653
- UniProt
- Q92686
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