STEAP4 Protein (AA 1-152) (His tag)

Produktnummer ABIN5853589

Produktdetails

Target: STEAP4 (STEAP Family Member 4 (STEAP4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-152

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses STEAP4 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMEKT CIDALPLTMN SSEKQETVCI FGTGDFGRSL GLKMLQCGYS VVFGSRNPQK TTLLPSGAEV LSYSEAAKKS GIIIIAIHRE HYDFLTELTE VLNGKILVDI SNNLKINQYP ESNAEYLAHL VPGAHVVKAF NTISAWALQS GALDASRQ

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Denatured

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M uREA, 10 % glycerol

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: STEAP4 (STEAP Family Member 4 (STEAP4))

Andere Bezeichnung: STEAP4 (STEAP4 Produkte)

Synonyme: STAMP2 Protein, TIARP Protein, TNFAIP9 Protein, MGC68826 Protein, STEAP4 Protein, MGC108044 Protein, steap4 Protein, 1110021O17Rik Protein, AI481214 Protein, Tiarp Protein, Tnfaip9 Protein, si:dkey-53p21.1 Protein, zgc:112143 Protein, STEAP4 metalloreductase Protein, STEAP4 metalloreductase L homeolog Protein, metalloreductase STEAP4 Protein, STEAP family member 4 Protein, STEAP4 Protein, steap4.L Protein, Steap4 Protein, steap4 Protein, LOC100136336 Protein, LOC100353852 Protein

Hintergrund: STEAP4 belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+),using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Recombinant human STEAP4 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molekulargewicht: 20.6kDa (188aa)

NCBI Accession: NP_078912

UniProt: Q687X5

Pathways: Transition Metal Ion Homeostasis