C1GALT1 Protein (AA 30-363) (His tag)

Produktnummer ABIN7280327

Produktdetails

Target: C1GALT1 (Core 1 Synthase, Glycoprotein-N-Acetylgalactosamine 3-beta-Galactosyltransferase, 1 (C1GALT1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 30-363

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses C1GALT1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSLLGEKVD TQPNVLHNDP HARHSDDNGQ NHLEGQMNFN ADSSQHKDEN TDIAENLYQK VRILCWVMTG PQNLEKKAKH VKATWAQRCN KVLFMSSEEN KDFPAVGLKT KEGRDQLYWK TIKAFQYVHE HYLEDADWFL KADDDTYVIL DNLRWLLSKY DPEEPIYFGR RFKPYVKQGY MSGGAGYVLS KEALKRFVDA FKTDKCTHSS SIEDLALGRC MEIMNVEAGD SRDTIGKETF HPFVPEHHLI KGYLPRTFWY WNYNYYPPVE GPGCCSDLAV SFHYVDSTTM YELEYLVYHL RPYGYLYRYQ PTLPERILKE ISQANKNEDT KVKLGNP

Reinheit: > 80 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1  mM DTT

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: C1GALT1 (Core 1 Synthase, Glycoprotein-N-Acetylgalactosamine 3-beta-Galactosyltransferase, 1 (C1GALT1))

Andere Bezeichnung: C1GALT1 (C1GALT1 Produkte)

Synonyme: C1GALT Protein, T-synthase Protein, 2210410E06Rik Protein, AV284120 Protein, c1galt1 Protein, fa98f05 Protein, zgc:66485 Protein, wu:fa98f05 Protein, C1GALT1 Protein, C1GalT1-A Protein, Core 1 beta3-Gal-T1-A Protein, wu:fi11c09 Protein, zgc:153355 Protein, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Protein, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 L homeolog Protein, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 Protein, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1b Protein, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a Protein, C1GALT1 Protein, LOC100496837.L Protein, C1galt1 Protein, c1galt1b Protein, c1galt1a Protein

Hintergrund: C1GALT1 generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from uDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this gene plays a key role in thrombopoiesis and kidney homeostasis. Recombinant human C1GALT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 41.4 kDa (357aa), confirmed by MALDI-TOF

NCBI Accession: NP_064541

UniProt: Q9NS00