ACOT8 Protein (AA 1-319) (His tag)
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- Target Alle ACOT8 Proteine anzeigen
- ACOT8 (Acyl-CoA Thioesterase 8 (ACOT8))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-319
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses ACOT8 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MGSSHHHHHH SSGLVPRGSH MGSMSSPQAP EDGQGCGDRG DPPGDLRSVL VTTVLNLEPL DEDLFRGRHY WVPAKRLFGG QIVGQALVAA AKSVSEDVHV HSLHCYFVRA GDPKLPVLYQ VERTRTGSSF SVRSVKAVQH GKPIFICQAS FQQAQPSPMQ HQFSMPTVPP PEELLDCETL IDQYLRDPNL QKRYPLALNR IAAQEVPIEI KPVNPSPLSQ LQRMEPKQMF WVRARGYIGE GDMKMHCCVA AYISDYAFLG TALLPHQWQH KVHFMVSLDH SMWFHAPFRA DHWMLYECES PWAGGSRGLV HGRLWRQDGV LAVTCAQEGV IRVKPQVSES KL
- Reinheit
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product ACOT8 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.2M NaCl, 40 % glycerol, 2 mM DTT
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- ACOT8 (Acyl-CoA Thioesterase 8 (ACOT8))
- Andere Bezeichnung
- ACOT8 (ACOT8 Produkte)
- Synonyme
- PTE1 Protein, zgc:101691 Protein, HNAACTE Protein, PTE-1 Protein, PTE-2 Protein, PTE2 Protein, hACTE-III Protein, hTE Protein, Pte1 Protein, acyl-CoA thioesterase 8 Protein, ACOT8 Protein, acot8 Protein, Acot8 Protein
- Hintergrund
- Acyl-coenzyme A thioesterase 8, also known as ACOT8, are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. This protein may mediate Nef-induced down-regulation of CD4. It competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). ACOT8 shows a preference for medium-length fatty acyl-CoAs. Recombinant human ACOT8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molekulargewicht
- 38.3 kDa (342aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_005460
- UniProt
- O14734
- Pathways
- Monocarboxylic Acid Catabolic Process
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