CPOX Protein (AA 111-454) (His tag)

Produktnummer ABIN5852918

Produktdetails

Target: CPOX (Coproporphyrinogen Oxidase (CPOX))

Protein-Typ: Recombinant

Proteineigenschaft: AA 111-454

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CPOX Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSTSLGRPE EEEDELAHRC SSFMAPPVTD LGELRRRPGD MKTKMELLIL ETQAQVCQAL AQVDGGANFS VDRWERKEGG GGISCVLQDG CVFEKAGVSI SVVHGNLSEE AAKQMRSRGK VLKTKDGKLP FCAMGVSSVI HPKNPHAPTI HFNYRYFEVE EADGNKQWWF GGGCDLTPTY LNQEDAVHFH RTLKEACDQH GPDLYPKFKK WCDDYFFIAH RGERRGIGGI FFDDLDSPSK EEVFRFVQSC ARAVVPSYIP LVKKHCDDSF TPQEKLWQQL RRGRYVEFNL LYDRGTKFGL FTPGSRIESI LMSLPLTARW EYMHSPSENS KEAEILEVLR HPRDWVR

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CPOX (Coproporphyrinogen Oxidase (CPOX))

Andere Bezeichnung: CPOX (CPOX Produkte)

Synonyme: CPO Protein, CPX Protein, Cpo Protein, cpo Protein, cb535 Protein, sb:cb535 Protein, wu:fc43a01 Protein, DDBDRAFT_0188158 Protein, DDBDRAFT_0231414 Protein, DDB_0188158 Protein, DDB_0231414 Protein, BcDNA:GM14838 Protein, CG3433 Protein, Dmel\\CG3433 Protein, l(2)k10617 Protein, l(2)k11018 Protein, coproporphyrinogen oxidase Protein, coproporphyrinogen III oxidase Protein, Coproporphyrinogen oxidase Protein, CPOX Protein, Cpox Protein, cpox Protein, hemF Protein, Coprox Protein, CNE00980 Protein, Shewana3_4102 Protein, HemF_3 Protein, Vapar_2685 Protein, Dd586_0781 Protein, BC1002_0909 Protein, Trad_0221 Protein, Bresu_2732 Protein, Galf_2657 Protein, BC1003_2365 Protein, Lbys_0733 Protein, Ftrac_1490 Protein, Astex_1139 Protein, BC1001_1038 Protein, Pedsa_0199 Protein, Fluta_2926 Protein, bgla_1g29750 Protein, Halhy_0288 Protein, Sphch_2673 Protein, Mesop_2259 Protein

Hintergrund: Coproporphyrinogen-III oxidase, mitochondrial precursor, also known as CPOX, is a 454 amino acid mitochondrial enzyme that is localized to the inner membrane space of erythrocytes. It participates in the sixth step of heme biosynthesis by catalyzing the formation of protoporphyrinogen IX from coproporphyrinogen III. Mutations in human CPOX gene predict the clinical outcome of the disease, with either hepatic hereditary coproporphyria or hematological manifestations of erythropoietic harderoporphyria. Recombinant human CPOX protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 41.6 kDa (367aa) confirmed by MALDI-TOF

NCBI Accession: NP_000088

UniProt: P36551