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HCST Protein (AA 20-48) (hIgG-His-tag)

HCST Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS Active
Produktnummer ABIN5778034
  • Target Alle HCST Proteine anzeigen
    HCST (Hematopoietic Cell Signal Transducer (HCST))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 20-48
    Spezies
    • 4
    • 1
    Human
    Quelle
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses HCST Protein ist gelabelt mit hIgG-His-tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    MGSSHHHHHH SSGLVPRGSH MHRHHPREMK KRVEDLHVGA TVAPSSRRDF TFDLYRALAS AAPSQNIFFS PVSISMSLAM LSLGAGSSTK MQILEGLGLN LQKSSEKELH RGFQQLLQEL NQPRDGFQLS LGNALFTDLV VDLQDTFVSA MKTLYLADTF PTNFRDSAGA MKQINDYVAK QTKGKIVDLL KNLDSNAVVI MVNYIFFKAK WETSFNHKGT QEQDFYVTSE TVVRVPMMSR EDQYHYLLDR NLSCRVVGVP YQGNATALFI LPSEGKMQQV ENGLSEKTLR KWLKMFKKRQ LELYLPKFSI EGSYQLEKVL PSLGISNVFT SHADLSGISN HSNIQVSEMV HKAVVEVDES GTRAAAATGT IFTFRSARLN SQRLVFNRPF LMFIVDNNIL FLGKVNRP
    Reinheit
    > 90 % by SDS - PAGE
    Biological Activity Comment
    Measured by its ability to inhibit Thrombin cleavage of substrate Boc-VPR-AMC. The IC50 for this effect is less or equal to 2 nM
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    Discover our top product HCST Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Liquid. In 20 mM MES buffer (  pH 6.0) containing 150  mM NaCl, 10 % glycerol
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    HCST (Hematopoietic Cell Signal Transducer (HCST))
    Andere Bezeichnung
    HCST (HCST Produkte)
    Synonyme
    DAP10 Protein, KAP10 Protein, PIK3AP Protein, Dap10 Protein, HCST Protein, dap10 Protein, dap10-A Protein, hcst Protein, hcsta Protein, kap10 Protein, pik3ap Protein, hematopoietic cell signal transducer Protein, hematopoietic cell signal transducer L homeolog Protein, HCST Protein, Hcst Protein, hcst Protein, hcst.L Protein
    Hintergrund
    Serpin A5, also known as PCI (Protein C Inhibitor) or PAI3 (plasminogen activator inhibitor 3), is a member of the serpin serine proteinase inhibitor family. This protein inhibits plasminogen activators as well as activated protein C. Serpin A5 is secreted in plasma, but is also expressed in liver. Serpin A5 is involved in cell inflammation, proliferation, apoptosis, tumor cell migration, invasion, and metastasis. Recombinant Serpin A5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molekulargewicht
    45.9 kDa (408aa), confirmed by MALDI-TOF
    UniProt
    P05154
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