Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

TFPI2 Protein (His tag)

TFPI2 Spezies: Human Wirt: Tobacco (Nicotiana benthamiana) Recombinant > 97 % by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue. Func
Produktnummer ABIN573781
  • Target Alle TFPI2 Proteine anzeigen
    TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))
    Protein-Typ
    Recombinant
    Spezies
    • 9
    • 4
    • 3
    • 2
    Human
    Quelle
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    Tobacco (Nicotiana benthamiana)
    Aufreinigungstag / Konjugat
    Dieses TFPI2 Protein ist gelabelt mit His tag.
    Applikation
    Functional Studies (Func)
    Sequenz
    HHHHHHGAAQ EPTGNNAEIC LLPLDYGPCK ALLLRYYYDR YTQSCRQFLY GGCEGNANNF YTWEACDDAC WRIEKVPKV
    Produktmerkmale
    Molecular formula: C407H592N116O117S6.
    Isoelectric Point: 6,25.
    Extinction coefficient: E 0.1 % (1g/L) = 2.35 (A 280 nm).
    This product contains no animal-derived components or impurities. It is produced by transient expression in non-transgenic plants.
    Aufreinigung
    Recombinant AGV212 includes a 6 His-tag at the N-terminal end, is purified by sequential chromatography (FPLC).
    Reinheit
    > 97 % by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.
    Endotoxin-Niveau
    < 0.04 EU/µg protein (LAL method)
  • Applikationshinweise
    The ability to prevent the hydrolysis of benzoyl-Larginine ethyl ester hydrochloride by trypsin.
    Kommentare

    Biological Activity: The activity of the inhibitor is expressed as the amount of trypsin inhibited per milligram of inhibitor. The ability to prevent the hydrolysis of benzoyl-L-arginine ethyl ester hydrochloride by trypsin is measured by spectrophotometer. One mg protein will inhibit 1-1.5 mg trypsin with activity of approximately 1000 BAEE units per mg protein.
    Synonyms: First Kunitz domain of the human Tissue Factor Protein Inhibitor 2 (TFPI-2) protein, AGV 212

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Lyophilized protein should be reconstituted adding 1 mL of sterile water to the vial, which gives a concentration of 1 mg of protease inhibitor per mL. At higher concentrations the solubility may be reduced and multimers generated. Optimal concentration should be determined for specific application and cell lines.
    Konzentration
    50 ng/µL
    Buffer
    PBS, pH 7.1.
    Lagerung
    4 °C
  • Target
    TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))
    Andere Bezeichnung
    TFPI-2 (TFPI2 Produkte)
    Synonyme
    MGC68843 Protein, TFPI2 Protein, MGC108301 Protein, si:ch211-262k23.2 Protein, tfpi2 Protein, PP5 Protein, REF1 Protein, TFPI-2 Protein, AV000670 Protein, PP5/TFPI-2 Protein, tissue factor pathway inhibitor 2 L homeolog Protein, tissue factor pathway inhibitor 2 Protein, tfpi2.L Protein, TFPI2 Protein, tfpi2 Protein, Tfpi2 Protein
    Hintergrund
    Recombinant human TFPI-2 doman 1 or AGV 212 is a protease inhibitor peptide generated from the first Kunitz domain of the human Tissue Factor Protein Inhibitor 2 (TFPI-2) protein, after site-directed mutagenesis to increase its activity. It is arranged in a single polypeptide chain that is linked by three disulfide bridges. AGV 212 is quite stable and inhibits trypsin with high efficiency and Ki lower than TFPI-2 one. TFPI-2 has been shown to inhibit Endothelial Cell Matrix (ECM) proteases essential for angiogenesis and metastasis.
    Molekulargewicht
    9.3 kDa
Sie sind hier:
Kundenservice