C10orf2 Protein (AA 32-684) (His tag)

Produktnummer ABIN5714434

Produktdetails

Target: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 32-684

Spezies: Human

Quelle: Hefe

Aufreinigungstag / Konjugat: Dieses C10orf2 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: APGPPRRRYR KETLQALDMP VLPVTATEIR QYLRGHGIPF QDGHSCLRAL SPFAESSQLK GQTGVTTSFS LFIDKTTGHF LCMTSLAEGS WEDFQASVEG RGDGAREGFL LSKAPEFEDS EEVRRIWNRA IPLWELPDQE EVQLADTMFG LTKVTDDTLK RFSVRYLRPA RSLVFPWFSP GGSGLRGLKL LEAKCQGDGV SYEETTIPRP SAYHNLFGLP LISRRDAEVV LTSRELDSLA LNQSTGLPTL TLPRGTTCLP PALLPYLEQF RRIVFWLGDD LRSWEAAKLF ARKLNPKRCF LVRPGDQQPR PLEALNGGFN LSRILRTALP AWHKSIVSFR QLREEVLGEL SNVEQAAGLR WSRFPDLNRI LKGHRKGELT VFTGPTGSGK TTFISEYALD LCSQGVNTLW GSFEISNVRL ARVMLTQFAE GRLEDQLDKY DHWADRFEDL PLYFMTFHGQ QSIRTVIDTM QHAVYVYDIC HVIIDNLQFM MGHEQLSTDR IAAQDYIIGV FRKFATDNNC HVTLVIHPRK EDDDKELQTA SIFGSAKASQ EADNVLILQD RKLVTGPGKR YLQVSKNRFD GDVGVFPLEF NKNSLTFSIP PKNKARLKKI KDDTGPVAKK PSSGKKGATT QNSEICSGQA PTPDQPDTSK RSK

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Andere Bezeichnung: PEO1 (C10ORF2 Produkte)

Synonyme: ATXN8 Protein, IOSCA Protein, MTDPS7 Protein, PEO Protein, PEO1 Protein, PEOA3 Protein, SANDO Protein, SCA8 Protein, TWINL Protein, C6H10orf2 Protein, D19Ertd626e Protein, Twinl Protein, twinkle mtDNA helicase L homeolog Protein, twinkle mtDNA helicase Protein, twnk.L Protein, TWNK Protein, Twnk Protein

Hintergrund: Involved in mitochondrial DNA (mtDNA) metabolism. Could function as an adenine nucleotide-dependent DNA helicase. Function inferred to be critical for lifetime maintenance of mtDNA integrity. In vitro, forms in combination with POLG, a processive replication machinery, which can use double-stranded DNA (dsDNA) as tplate to synthesize single-stranded DNA (ssDNA) molecules. May be a key regulator of mtDNA copy number in mammals.

Molekulargewicht: 75.45 kDa

UniProt: Q96RR1