Major Royal Jelly Protein 1 (MRJP1) (AA 20-432) protein (His tag)

Produktnummer ABIN5714288

Produktdetails

Target: Major Royal Jelly Protein 1 (MRJP1)

Protein-Typ: Recombinant

Proteineigenschaft: AA 20-432

Spezies: Apis mellifera

Quelle: Hefe

Aufreinigungstag / Konjugat: His tag

Applikation: SDS-PAGE (SDS)

Sequenz: NILRGESLNK SLPILHEWKF FDYDFGSDER RQDAILSGEY DYKNNYPSDI DQWHDKIFVT MLRYNGVPSS LNVISKKVGD GGPLLQPYPD WSFAKYDDCS GIVSASKLAI DKCDRLWVLD SGLVNNTQPM CSPKLLTFDL TTSQLLKQVE IPHDVAVNAT TGKGRLSSLA VQSLDCNTNS DTMVYIADEK GEGLIVYHNS DDSFHRLTSN TFDYDPKFTK MTIDGESYTA QDGISGMALS PMTNNLYYSP VASTSLYYVN TEQFRTSDYQ QNDIHYEGVQ NILDTQSSAK VVSKSGVLFF GLVGDSALGC WNEHRTLERH NIRTVAQSDE TLQMIASMKI KEALPHVPIF DRYINREYIL VLSNKMQKMV NNDFNFDDVN FRIMNANVNE LILNTRCENP DNDRTPFKIS IHL

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: Major Royal Jelly Protein 1 (MRJP1)

Andere Bezeichnung: MRJP1 (MRJP1 Produkte)

Synonyme: GB14888 Protein, MRJP-1 Protein, p56kP-4 Protein, major royal jelly protein 1 Protein, Mrjp1 Protein

Hintergrund: Major royal jelly protein 1: induces the differentiation of honeybee larvae into queens through an Egfr-mediated signaling pathway. Promotes body size increase by activating p70 S6 kinase, stimulates ovary development by augmenting the titer of vitellogenin (Vg) and juvenile hormone, and reduces developmental time by increasing the activity of mitogen-activated protein kinase and inducing the 20-hydroxyecdysone protein (20E). Most abundant protein found in the royal jelly which is the food of the queen honey bee larva. The royal jelly determines the development of the young larvae and is responsible for the high reproductive ability of the honeybee queen.Jellein-1: has antibacterial activity against the Gram-positive bacteria S.aureus ATCC 6535, S.saprophyticus and B.subtilis CCT2471, and the Gram-negative bacteria E.coli CCT1371, E.cloacae ATCC 23355, K.pneumoniae ATCC 13883 and P.aeruginosa ATCC 27853, and antifungal activity against C.albicans. Lack cytolytic activity and does not induce rat peritoneal mast cell degranulation.Jellein-2: has antibacterial activity against the Gram-positive bacteria S.aureus ATCC 6535, S.saprophyticus and B.subtilis CCT2471, and the Gram-negative bacteria E.coli CCT1371, E.cloacae ATCC 23355, K.pneumoniae ATCC 13883 and P.aeruginosa ATCC 27853, and antifungal activity against C.albicans. Lack cytolytic activity and does not induce rat peritoneal mast cell degranulation.Jellein-4: lacks antibacterial and antifungal activity. Lacks cytolytic activity and does not induce rat peritoneal mast cell degranulation.

Molekulargewicht: 48.8 kDa

UniProt: O18330