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UGT1A1 Protein (AA 26-533) (His tag)

UGT1A1 Spezies: Human Wirt: Hefe Recombinant > 90 % SDS
Produktnummer ABIN5713928
  • Target Alle UGT1A1 Proteine anzeigen
    UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 26-533
    Spezies
    • 4
    • 2
    Human
    Quelle
    • 3
    • 1
    • 1
    • 1
    Hefe
    Aufreinigungstag / Konjugat
    Dieses UGT1A1 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    HAGKILLIPV DGSHWLSMLG AIQQLQQRGH EIVVLAPDAS LYIRDGAFYT LKTYPVPFQR EDVKESFVSL GHNVFENDSF LQRVIKTYKK IKKDSAMLLS GCSHLLHNKE LMASLAESSF DVMLTDPFLP CSPIVAQYLS LPTVFFLHAL PCSLEFEATQ CPNPFSYVPR PLSSHSDHMT FLQRVKNMLI AFSQNFLCDV VYSPYATLAS EFLQREVTVQ DLLSSASVWL FRSDFVKDYP RPIMPNMVFV GGINCLHQNP LSQEFEAYIN ASGEHGIVVF SLGSMVSEIP EKKAMAIADA LGKIPQTVLW RYTGTRPSNL ANNTILVKWL PQNDLLGHPM TRAFITHAGS HGVYESICNG VPMVMMPLFG DQMDNAKRME TKGAGVTLNV LEMTSEDLEN ALKAVINDKS YKENIMRLSS LHKDRPVEPL DLAVFWVEFV MRHKGAPHLR PAAHDLTWYQ YHSLDVIGFL LAVVLTVAFI TFKCCAYGYR KCLGKKGRVK KAHKSKTH
    Aufreinigung
    SDS-PAGE
    Reinheit
    > 90 %
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Lagerung
    -80 °C,4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
    Andere Bezeichnung
    UD11 (UGT1A1 Produkte)
    Synonyme
    BILIQTL1 Protein, GNT1 Protein, HUG-BR1 Protein, UDPGT Protein, UDPGT 1-1 Protein, UGT1 Protein, UGT1A Protein, Gnt1 Protein, UGT1A01 Protein, Udpgt-1a Protein, UgtBr1 Protein, Udpgt Protein, Ugt1 Protein, zgc:123097 Protein, UDP glucuronosyltransferase family 1 member A1 Protein, UDP glucuronosyltransferase 1 family, polypeptide A1 Protein, UDP-glucuronosyltransferase 1-1 Protein, UDP-glucuronosyltransferase Protein, UDP-glucuronosyltransferase 1-6 Protein, UDP glucuronosyltransferase 1 family polypeptide a1 Protein, UGT1A1 Protein, Ugt1a1 Protein, LOC100065342 Protein, LOC100125517 Protein, LOC100229734 Protein, LOC100405984 Protein, LOC100511479 Protein, ugt1a1 Protein
    Hintergrund
    UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Is also able to catalyze the glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1.
    Molekulargewicht
    59.1 kDa
    UniProt
    P22309
    Pathways
    Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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