MME Protein (AA 52-750) (His tag)
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- Target Alle MME Proteine anzeigen
- MME (Membrane Metallo-Endopeptidase (MME))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 52-750
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Spezies
- Human
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Quelle
- Hefe
- Aufreinigungstag / Konjugat
- Dieses MME Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- YDDGICKSSD CIKSAARLIQ NMDATTEPCT DFFKYACGGW LKRNVIPETS SRYGNFDILR DELEVVLKDV LQEPKTEDIV AVQKAKALYR SCINESAIDS RGGEPLLKLL PDIYGWPVAT ENWEQKYGAS WTAEKAIAQL NSKYGKKVLI NLFVGTDDKN SVNHVIHIDQ PRLGLPSRDY YECTGIYKEA CTAYVDFMIS VARLIRQEER LPIDENQLAL EMNKVMELEK EIANATAKPE DRNDPMLLYN KMTLAQIQNN FSLEINGKPF SWLNFTNEIM STVNISITNE EDVVVYAPEY LTKLKPILTK YSARDLQNLM SWRFIMDLVS SLSRTYKESR NAFRKALYGT TSETATWRRC ANYVNGNMEN AVGRLYVEAA FAGESKHVVE DLIAQIREVF IQTLDDLTWM DAETKKRAEE KALAIKERIG YPDDIVSNDN KLNNEYLELN YKEDEYFENI IQNLKFSQSK QLKKLREKVD KDEWISGAAV VNAFYSSGRN QIVFPAGILQ PPFFSAQQSN SLNYGGIGMV IGHEITHGFD DNGRNFNKDG DLVDWWTQQS ASNFKEQSQC MVYQYGNFSW DLAGGQHLNG INTLGENIAD NGGLGQAYRA YQNYIKKNGE EKLLPGLDLN HKQLFFLNFA QVWCGTYRPE YAVNSIKTDV HSPGNFRIIG TLQNSAEFSE AFHCRKNSYM NPEKKCRVW
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
- Top Product
- Discover our top product MME Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- MME (Membrane Metallo-Endopeptidase (MME))
- Andere Bezeichnung
- NEP (MME Produkte)
- Synonyme
- CALLA Protein, CD10 Protein, NEP Protein, SFE Protein, 6030454K05Rik Protein, C85356 Protein, Nep Protein, neprilysin Protein, membrane metalloendopeptidase Protein, membrane metallo endopeptidase Protein, membrane metallo-endopeptidase Protein, MME Protein, Mme Protein
- Substanzklasse
- Chemical
- Hintergrund
- Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids . Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond . Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 . Involved in the degradation of atrial natriuretic factor (ANF) . Displays UV-inducible elastase activity toward skin preelastic and elastic fibers .
- Molekulargewicht
- 81.83 kDa
- UniProt
- P08473
- Pathways
- RTK Signalweg, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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