CK1 epsilon Protein (AA 1-416, full length) (His tag)

Produktnummer ABIN5713380

Produktdetails

Target: CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))

Protein-Typ: Recombinant

Proteineigenschaft: full length, AA 1-416

Spezies: Human

Quelle: Hefe

Aufreinigungstag / Konjugat: Dieses CK1 epsilon Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MELRVGNKYR LGRKIGSGSF GDIYLGANIA SGEEVAIKLE CVKTKHPQLH IESKFYKMMQ GGVGIPSIKW CGAEGDYNVM VMELLGPSLE DLFNFCSRKF SLKTVLLLAD QMISRIEYIH SKNFIHRDVK PDNFLMGLGK KGNLVYIIDF GLAKKYRDAR THQHIPYREN KNLTGTARYA SINTHLGIEQ SRRDDLESLG YVLMYFNLGS LPWQGLKAAT KRQKYERISE KKMSTPIEVL CKGYPSEFST YLNFCRSLRF DDKPDYSYLR QLFRNLFHRQ GFSYDYVFDW NMLKFGAARN PEDVDRERRE HEREERMGQL RGSATRALPP GPPTGATANR LRSAAEPVAS TPASRIQPAG NTSPRAISRV DRERKVSMRL HRGAPANVSS SDLTGRQEVS RIPASQTSVP FDHLGK

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))

Andere Bezeichnung: KC1E (CSNK1E Produkte)

Synonyme: CKIepsilon Protein, HCKIE Protein, CKIe Protein, ck1-epsilon Protein, ck1epsilon Protein, hckie Protein, dco Protein, fj38c01 Protein, wu:fj38c01 Protein, wu:fj62a04 Protein, zgc:77310 Protein, AI426939 Protein, AI551861 Protein, AW457082 Protein, CK1epsilon Protein, KC1epsilon Protein, tau Protein, ckie Protein, CSNK1E Protein, Csnk1e Protein, CKI-epsilon Protein, 0538/13 Protein, 0915/10 Protein, 1396/02 Protein, 1447/01 Protein, 1460/09 Protein, CG2048 Protein, CK1delta/epsilon Protein, DBT Protein, DBT/CK1epsilon Protein, DCO Protein, DCO/CKIe Protein, Dbt Protein, Dco Protein, Dco/CK1 Protein, Dmel\CG2048 Protein, dCKIepsilon Protein, dbt Protein, dco-1 Protein, ddbt Protein, l(3)S053813 Protein, l(3)S144701 Protein, l(3)dco Protein, l(3)dco-1 Protein, l(3)discs overgrown Protein, l(3)discs overgrown-1 Protein, l(3)j3B9 Protein, l(3)rK215 Protein, casein kinase 1 epsilon Protein, casein kinase 1, epsilon Protein, casein kinase 1 epsilon L homeolog Protein, casein kinase I isoform epsilon Protein, casein kinase I epsilon Protein, casein kinase I Protein, LOC400927-CSNK1E readthrough Protein, discs overgrown Protein, CSNK1E Protein, csnk1e Protein, Csnk1e Protein, csnk1e.L Protein, LOC443240 Protein, NAEGRDRAFT_82890 Protein, LOC100407384 Protein, LOC100523244 Protein, LOC100607246 Protein, LOC100727500 Protein, LOC400927-CSNK1E Protein, dco Protein

Hintergrund: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.

Molekulargewicht: 49.3 kDa

UniProt: P49674

Pathways: Hedgehog Signalweg, M Phase