CDC23 Protein (AA 14-591, partial) (His tag)

Produktnummer ABIN5711947

Produktdetails

Target: CDC23 (Cell Division Cycle 23 (CDC23))

Protein-Typ: Recombinant

Proteineigenschaft: AA 14-591, partial

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CDC23 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: LSINSDFSDL REIKKQLLLI AGLTRERGLL HSSKWSAELA FSLPALPLAE LQPPPPITEE DAQDMDAYTL AKAYFDVKEY DRAAHFLHGC NSKKAYFLYM YSRYLSGEKK KDDETVDSLG PLEKGQVKNE ALRELRVELS KKHQARELDG FGLYLYGVVL RKLDLVKEAI DVFVEATHVL PLHWGAWLEL CNLITDKEML KFLSLPDTWM KEFFLAHIYT ELQLIEEALQ KYQNLIDVGF SKSSYIVSQI AVAYHNIRDI DKALSIFNEL RKQDPYRIEN MDTFSNLLYV RSMKSELSYL AHNLCEIDKY RVETCCVIGN YYSLRSQHEK AALYFQRALK LNPRYLGAWT LMGHEYMEMK NTSAAIQAYR HAIEVNKRDY RAWYGLGQTY EILKMPFYCL YYYRRAHQLR PNDSRMLVAL GECYEKLNQL VEAKKCYWRA YAVGDVEKMA LVKLAKLHEQ LTESEQAAQC YIKYIQDIYS CGEIVEHLEE STAFRYLAQY YFKCKLWDEA STCAQKCCAF NDTREEGKAL LRQILQLRNQ GETPTTEVPA PFFLPASLSA NNTPTRRVSP LNLSSVTP

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: CDC23 (Cell Division Cycle 23 (CDC23))

Andere Bezeichnung: CDC23 (CDC23 Produkte)

Synonyme: CDC23 Protein, anaphase-promoting complex subunit 8 Protein, zgc:56013 Protein, 6030435O18 Protein, D18Ertd243e Protein, ANAPC8 Protein, APC8 Protein, CUT23 Protein, cell division cycle 23 Protein, cell division cycle protein 23 homolog Protein, anaphase-promoting complex subunit 8 Protein, CDC23 (cell division cycle 23, yeast, homolog) Protein, cell division cycle 23 S homeolog Protein, CDC23 cell division cycle 23 Protein, CDC23 Protein, LOC100162672 Protein, LOC100380698 Protein, APC8 Protein, cdc23 Protein, cdc23.S Protein, Cdc23 Protein

Hintergrund: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Molekulargewicht: 71.1 kDa

UniProt: Q9UJX2

Pathways: Protein targeting to Nucleus