SCRIB Protein (AA 33-443) (His-SUMO Tag)

Produktnummer ABIN5711627

Produktdetails

Target: SCRIB (Scribbled Homolog (SCRIB))

Protein-Typ: Recombinant

Proteineigenschaft: AA 33-443

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses SCRIB Protein ist gelabelt mit His-SUMO Tag.

Applikation: SDS-PAGE (SDS)

Sequenz: PSLIKQQVLK NVRIDPSSLS FNMWKEIPIP FYLSVYFFDV MNPSEILKGE KPQVRERGPY VYREFRHKSN ITFNNNDTVS FLEYRTFQFQ PSKSHGSESD YIVMPNILVL GAAVMMENKP MTLKLIMTLA FTTLGERAFM NRTVGEIMWG YKDPLVNLIN KYFPGMFPFK DKFGLFAELN NSDSGLFTVF TGVQNISRIH LVDKWNGLSK VDFWHSDQCN MINGTSGQMW PPFMTPESSL EFYSPEACRS MKLMYKESGV FEGIPTYRFV APKTLFANGS IYPPNEGFCP CLESGIQNVS TCRFSAPLFL SHPHFLNADP VLAEAVTGLH PNQEAHSLFL DIHPVTGIPM NCSVKLQLSL YMKSVAGIGQ TGKIEPVVLP LLWFAESGAM EGETLHTFYT QLVLMPKVMH Y

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: SCRIB (Scribbled Homolog (SCRIB))

Andere Bezeichnung: SCRB1 (SCRIB Produkte)

Synonyme: 0424/05 Protein, CG31082 Protein, CG42614 Protein, CG43398 Protein, CG5462 Protein, CG5467 Protein, CT17324 Protein, Dmel\\CG43398 Protein, Dmel_CG31082 Protein, Dmel_CG42614 Protein, Dmel_CG5462 Protein, Dmel_CG5467 Protein, MENE (3R)-F Protein, SCR Protein, Scb Protein, Scrb Protein, Scrib Protein, ird Protein, ird15 Protein, l(3)673 Protein, l(3)S042405 Protein, l(3)c00119 Protein, l(3)j7B3 Protein, scrb Protein, smi97B Protein, vart Protein, AI118201 Protein, CRIB Protein, Crc Protein, SCRIB1 Protein, Scrb1 Protein, mKIAA0147 Protein, vartul Protein, scrb1 Protein, scribble Protein, scribble1 Protein, si:ch211-12p8.1 Protein, si:zc12p8.1 Protein, CRIB1 Protein, SCRB1 Protein, Vartul Protein, scribbled Protein, scribbled planar cell polarity Protein, scribbled planar cell polarity protein Protein, scrib Protein, Scrib Protein, SCRIB Protein

Hintergrund: Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma mbrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester .

Molekulargewicht: 62.64 kDa

UniProt: Q8WTV0

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Tube Formation, Synaptic Vesicle Exocytosis, Asymmetric Protein Localization