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IL29 Protein (AA 21-200, partial) (His-SUMO Tag)

IL29 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Produktnummer ABIN5711509
  • Target Alle IL29 Proteine anzeigen
    IL29 (Interleukin 29 (IL29))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 21-200, partial
    Spezies
    • 18
    • 1
    • 1
    Human
    Quelle
    • 10
    • 6
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses IL29 Protein ist gelabelt mit His-SUMO Tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    VPTSKPTTTG KGCHIGRFKS LSPQELASFK KARDALEESL KLKNWSCSSP VFPGNWDLRL LQVRERPVAL EAELALTLKV LEAAAGPALE DVLDQPLHTL HHILSQLQAC IQPQPTAGPR PRGRLHHWLH RLQEAPKKES AGCLEASVTF NLFRLLTRDL KYVADGNLCL RTSTHPEST-
    Aufreinigung
    SDS-PAGE
    Reinheit
    > 90 %
    Top Product
    Discover our top product IL29 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Lagerung
    -80 °C,4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    IL29 (Interleukin 29 (IL29))
    Andere Bezeichnung
    IFNL1 (IL29 Produkte)
    Synonyme
    IL-29 Protein, IL29 Protein, interferon lambda 1 Protein, interferon lambda-1 Protein, interleukin 29 (interferon, lambda 1) Protein, IFNL1 Protein, LOC612539 Protein, IL29 Protein
    Hintergrund
    Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagent leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
    Molekulargewicht
    35.85 kDa
    UniProt
    Q8IU54
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