IL29 Protein (AA 21-200, partial) (His-SUMO Tag)
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- Target Alle IL29 Proteine anzeigen
- IL29 (Interleukin 29 (IL29))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 21-200, partial
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses IL29 Protein ist gelabelt mit His-SUMO Tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- VPTSKPTTTG KGCHIGRFKS LSPQELASFK KARDALEESL KLKNWSCSSP VFPGNWDLRL LQVRERPVAL EAELALTLKV LEAAAGPALE DVLDQPLHTL HHILSQLQAC IQPQPTAGPR PRGRLHHWLH RLQEAPKKES AGCLEASVTF NLFRLLTRDL KYVADGNLCL RTSTHPEST-
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
- Top Product
- Discover our top product IL29 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- IL29 (Interleukin 29 (IL29))
- Andere Bezeichnung
- IFNL1 (IL29 Produkte)
- Synonyme
- IL-29 Protein, IL29 Protein, interferon lambda 1 Protein, interferon lambda-1 Protein, interleukin 29 (interferon, lambda 1) Protein, IFNL1 Protein, LOC612539 Protein, IL29 Protein
- Hintergrund
- Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagent leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
- Molekulargewicht
- 35.85 kDa
- UniProt
- Q8IU54
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