PLCz1 Protein (AA 1-415, partial) (His-SUMO Tag)
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- Target Alle PLCz1 Proteine anzeigen
- PLCz1 (Phospholipase C zeta 1 (PLCz1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- partial, AA 1-415
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses PLCz1 Protein ist gelabelt mit His-SUMO Tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MEMRWFLSKI QDDFRGGKIN LEKTQRLLEK LDIRCSYIHV KQIFKTSDYP VVLSLENHCS TAQQEVMADN LQATFGESLL SDMLDDFPDT LPSPEALKFK ILVKNKKIGT LKETHERKGS DKRGDNQDKE TGVKKLPGVM LFKKKKTRKL KIALALSDLV IYTKAEKFKS FQHSRLYQQF NENNSIGETQ ARKLSKLRVH EFIFHTRKFI TRIYPKATRA DSSNFNPQEF WNIGCQMVAL NFQTPGLPMD LQNGKFLDNG GSGYILKPHF LRESKSYFNP SNIKEGMPIT LTIRLISGIQ LPLTHSSSNK GDSLVIIEVF GVPNDQMKQQ TRVIKKNAFS PRWNETFTFI IHVPELALIR FVVEGQGLIA GNEFLGQYTL PLLCMNKGYR RIPLFSRMGE SLEPASLFVY VWYVR
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
- Top Product
- Discover our top product PLCz1 Protein
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Phospholipase C zeta 1 (PLCz1) (AA 322-572) protein (His-IF2DI Tag)
PLCz1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Phospholipase C zeta 1 (PLCz1) (AA 1-647) protein (Strep Tag)Crystallography grade PLCz1 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Phospholipase C zeta 1 (PLCz1) (AA 1-608) protein (Strep Tag)Crystallography grade PLCz1 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- PLCz1 (Phospholipase C zeta 1 (PLCz1))
- Andere Bezeichnung
- PLCZ1 (PLCz1 Produkte)
- Synonyme
- PLC-zeta-1 Protein, PLCZ1 Protein, 1700041H07Rik Protein, PLCzeta Protein, NYD-SP27 Protein, PLCZ Protein, phospholipase C zeta 1 Protein, phospholipase C, zeta 1 Protein, PLCZ1 Protein, Plcz1 Protein
- Hintergrund
- The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca2+-dependent manner. Triggers intracellular Ca2+ oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating bryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete mbrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.
- Molekulargewicht
- 63.7 kDa
- UniProt
- Q86YW0
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