RRM1 Protein (AA 1-761, full length) (His-SUMO Tag)

Produktnummer ABIN5710974

Produktdetails

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Protein-Typ: Recombinant

Proteineigenschaft: full length, AA 1-761

Spezies: E. coli

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses RRM1 Protein ist gelabelt mit His-SUMO Tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MNQNLLVTKR DGSTERINLD KIHRVLDWAA EGLHNVSISQ VELRSHIQFY DGIKTSDIHE TIIKAAADLI SRDAPDYQYL AARLAIFHLR KKAYGQFEPP ALYDHVVKMV EMGKYDNHLL EDYTEEEFKQ MDTFIDHDRD MTFSYAAVKQ LEGKYLVQNR VTGEIYESAQ FLYILVAACL FSNYPRETRL QYVKRFYDAV STFKISLPTP IMSGVRTPTR QFSSCVLIEC GDSLDSINAT SSAIVKYVSQ RAGIGINAGR IRALGSPIRG GEAFHTGCIP FYKHFQTAVK SCSQGGVRGG AATLFYPMWH LEVESLLVLK NNRGVEGNRV RHMDYGVQIN KLMYTRLLKG EDITLFSPSD VPGLYDAFFA DQEEFERLYT KYEKDDSIRK QRVKAVELFS LMMQERASTG RIYIQNVDHC NTHSPFDPAI APVRQSNLCL EIALPTKPLN DVNDENGEIA LCTLSAFNLG AINNLDELEE LAILAVRALD ALLDYQDYPI PAAKRGAMGR RTLGIGVINF AYYLAKHGKR YSDGSANNLT HKTFEAIQYY LLKASNELAK EQGACPWFNE TTYAKGILPI DTYKKDLDTI ANEPLHYDWE ALRESIKTHG LRNSTLSALM PSETSSQISN ATNGIEPPRG YVSIKASKDG ILRQVVPDYE HLHDAYELLW EMPGNDGYLQ LVGIMQKFID QSISANTNYD PSRFPSGKVP MQQLLKDLLT AYKFGVKTLY YQNTRDGAED AQDDLVPSIQ DDGCESGACK I

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Andere Bezeichnung: RIR1 (RRM1 Produkte)

Synonyme: CG5371 Protein, DmRNR1 Protein, Dmel\\CG5371 Protein, RNR1 Protein, RnrM1 Protein, RntL Protein, l(2)k06709 Protein, XRRM1 Protein, R1 Protein, RIR1 Protein, RR1 Protein, CHUNP6866 Protein, cb396 Protein, cb838 Protein, r1 Protein, sb:cb548 Protein, wu:fb39b07 Protein, wu:fi14b02 Protein, wu:fk95f07 Protein, ribonucleotide reductase catalytic subunit M1 Protein, Ribonucleoside diphosphate reductase large subunit Protein, ribonucleoside-diphosphate reductase large subunit Protein, ribonucleotide reductase M1 L homeolog Protein, ribonucleotide reductase M1 Protein, ribonucleotide reductase M1 polypeptide Protein, RRM1 Protein, RnrL Protein, LOC100472317 Protein, rrm1 Protein, rrm1.L Protein, Rrm1 Protein

Hintergrund: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines.

Molekulargewicht: 101.72 kDa

UniProt: P00452

Pathways: Positive Regulation of Endopeptidase Activity