Murinoglobulin 1 Protein (Mug1) (AA 700-910, partial) (His tag)

Produktnummer ABIN5710860

Produktdetails

Target: Murinoglobulin 1 (Mug1)

Protein-Typ: Recombinant

Proteineigenschaft: AA 700-910, partial

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Murinoglobulin 1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: TPEISWSLRT TLSKRPEEPP RKDPSSNDPL TETIRKYFPE TWVWDIVTVN STGLAEVEMT VPDTITEWKA GALCLSNDTG LGLSSVVPLQ AFKPFFVEVS LPYSVVRGEA FMLKATVMNY LPTSMQMSVQ LEASPDFTAV PVGDDQDSYC LSANGRHTSS WLVTPKSLGN VNFSVSAEAQ QSSEPCGSEV ATVPETGRKD TVVKVLIVEP E

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: Murinoglobulin 1 (Mug1)

Andere Bezeichnung: MUG1 (Mug1 Produkte)

Synonyme: murinoglobulin 1 Protein, Mug1 Protein

Hintergrund: A proteinase activates the inhibitor by specific proteolysis in the bait region, which, by an unknown mechanism leads to reaction at the cysteinyl-glutamyl internal thiol ester site and to a conformational change, whereby the proteinase is trapped and/or covalently bound to the inhibitor. While in the tetrameric proteinase inhibitors steric inhibition is sufficiently strong, monomeric forms need a covalent linkage between the activated glutamyl residue of the original thiol ester and a terminal amino group of a lysine or another nucleophilic group on the proteinase, for inhibition to be effective.

Molekulargewicht: 27.13 kDa

UniProt: P28665