TNFL6 Protein (AA 130-281, Extracellular) (His tag)

Produktnummer ABIN5709501

Produktdetails

Target: TNFL6 (Tumor Necrosis Factor Ligand Superfamily Member 6 (TNFL6))

Protein-Typ: Recombinant

Proteineigenschaft: Extracellular, AA 130-281

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses TNFL6 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: QIGHPSPPPE KKELRKVAHL TGKSNSRSMP LEWEDTYGIV LLSGVKYKKG GLVINETGLY FVYSKVYFRG QSCNNLPLSH KVYMRNSKYP QDLVMMEGKM MSYCTTGQMW ARSSYLGAVF NLTSADHLYV NVSELSLVNF EESQTFFGLY KL

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: TNFL6 (Tumor Necrosis Factor Ligand Superfamily Member 6 (TNFL6))

Andere Bezeichnung: TNFL6 (TNFL6 Produkte)

Hintergrund: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.

Molekulargewicht: 21.4 kDa

UniProt: P48023