BMPR1A Protein (AA 177-532) (His-SUMO Tag)

Produktnummer ABIN5709147

Produktdetails

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Protein-Typ: Recombinant

Proteineigenschaft: AA 177-532

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses BMPR1A Protein ist gelabelt mit His-SUMO Tag.

Applikation: SDS-PAGE (SDS)

Sequenz: KHYCKSISSR RRYNRDLEQD EAFIPVGESL KDLIDQSQSS GSGSGLPLLV QRTIAKQIQM VRQVGKGRYG EVWMGKWRGE KVAVKVFFTT EEASWFRETE IYQTVLMRHE NILGFIAADI KGTGSWTQLY LITDYHENGS LYDFLKCATL DTRALLKLAY SAACGLCHLH TEIYGTQGKP AIAHRDLKSK NILIKKNGSC CIADLGLAVK FNSDTNEVDV PLNTRVGTKR YMAPEVLDES LNKNHFQPYI MADIYSFGLI IWEMARRCIT GGIVEEYQLP YYNMVPSDPS YEDMREVVCV KRLRPIVSNR WNSDECLRAV LKLMSECWAH NPASRLTALR IKKTLAKMVE SQDVKI

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Andere Bezeichnung: BMR1A (BMPR1A Produkte)

Synonyme: 10q23del Protein, ACVRLK3 Protein, ALK3 Protein, CD292 Protein, SKR5 Protein, 1110037I22Rik Protein, AU045487 Protein, BMPR-IA Protein, Bmpr Protein, BMPR-1 Protein, BRK-1 Protein, BMPR1A Protein, acvrlk3 Protein, alk-3 Protein, alk3 Protein, cd292 Protein, skr5 Protein, BR1a Protein, alk3tr Protein, bmpr1a Protein, zgc:136731 Protein, wu:fe05b06 Protein, wu:fe06e10 Protein, zgc:92227 Protein, bone morphogenetic protein receptor type 1A Protein, bone morphogenetic protein receptor, type 1A Protein, bone morphogenetic protein receptor type 1A S homeolog Protein, bone morphogenetic protein receptor, type IAa Protein, bone morphogenetic protein receptor, type IAb Protein, BMPR1A Protein, Bmpr1a Protein, bmpr1a Protein, bmpr1a.S Protein, bmpr1aa Protein, bmpr1ab Protein

Hintergrund: On ligand binding, forms a receptor complex consisting of two type II and two type I transmbrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4. Positively regulates chondrocyte differentiation through GDF5 interaction .

Molekulargewicht: 56.57 kDa

UniProt: P36894

Pathways: Stem Cell Maintenance