Crystallography grade
AP1S3
Spezies: Human
Wirt: Tobacco (Nicotiana tabacum)
Recombinant
>80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
SDS, ELISA, WB
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.1-2 mg/mL
Buffer
20 mM Tris-HCl based buffer, pH 8.0
Lagerung
-80 °C,4 °C,-20 °C
Informationen zur Lagerung
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target
AP1S3
(Adaptor-Related Protein Complex 1, sigma 3 Subunit (AP1S3))
1190009B22 Protein, Jr2 Protein, [s]3A Protein, zgc:101676 Protein, zgc:112172 Protein, ap1s3 Protein, adaptor-related protein complex AP-1, sigma 3 Protein, adaptor related protein complex 1 sigma 3 subunit Protein, adaptor-related protein complex 1, sigma 3 subunit, b Protein, adaptor-related protein complex 1, sigma 3 subunit, a Protein, adaptor related protein complex 1 sigma 3 subunit S homeolog Protein, Ap1s3 Protein, AP1S3 Protein, ap1s3b Protein, ap1s3a Protein, ap1s3.S Protein
Hintergrund
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to mbranes and the recognition of sorting signals within the cytosolic tails of transmbrane cargo molecules. Involved in TLR3 trafficking .